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Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure

Author

Listed:
  • Virginie Lemiale
  • Guillaume Dumas
  • Alexandre Demoule
  • Frédéric Pène
  • Achille Kouatchet
  • Magali Bisbal
  • Saad Nseir
  • Laurent Argaud
  • Loay Kontar
  • Kada Klouche
  • François Barbier
  • Amélie Seguin
  • Guillaume Louis
  • Jean Michel Constantin
  • Julien Mayaux
  • Florent Wallet
  • Vincent Peigne
  • Christophe Girault
  • Johanna Oziel
  • Martine Nyunga
  • Nicolas Terzi
  • Lila Bouadma
  • Alexandre Lautrette
  • Naike Bige
  • Jean Herle Raphalen
  • Laurent Papazian
  • Fabrice Bruneel
  • Christine Lebert
  • Dominique Benoit
  • Anne-Pascale Meert
  • Samir Jaber
  • Djamel Mokart
  • Michael Darmon
  • Elie Azoulay

Abstract

Background: Delayed intubation is associated with high mortality. There is a lack of objective criteria to decide the time of intubation. We assessed a recently described combined oxygenation index (ROX index) to predict intubation in immunocompromised patients. The study is a secondary analysis of randomized trials in immunocompromised patients, including all patients who received high-flow nasal cannula (HFNC). The first objective was to evaluate the accuracy of the ROX index to predict intubation for patients with acute respiratory failure. Results: In the study, 302 patients received HFNC. Acute respiratory failure was mostly related to pneumonia (n = 150, 49.7%). Within 2 (1–3) days, 115 (38.1%) patients were intubated. The ICU mortality rate was 27.4% (n = 83). At 6 h, the ROX index was lower for patients who needed intubation compared with those who did not [4.79 (3.69–7.01) vs. 6.10 (4.48–8.68), p

Suggested Citation

  • Virginie Lemiale & Guillaume Dumas & Alexandre Demoule & Frédéric Pène & Achille Kouatchet & Magali Bisbal & Saad Nseir & Laurent Argaud & Loay Kontar & Kada Klouche & François Barbier & Amélie Seguin, 2021. "Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure," ULB Institutional Repository 2013/319122, ULB -- Universite Libre de Bruxelles.
    • Handle: RePEc:ulb:ulbeco:2013/319122
    Note: SCOPUS: ar.j
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