IDEAS home Printed from https://ideas.repec.org/p/ssa/lemwps/2019-32.html
   My bibliography  Save this paper

When authors become inventors: an empirical analysis on patent-paper pairs in medical research

Author

Listed:
  • Arianna Martinelli
  • Elena Romito

Abstract

This paper investigates the effect of patenting on follow-on knowledge in cancer research. Using a difference-in-difference approach on an original dataset of patent-paper-pairs we are able to estimate the causal effect of the granting of a patent on scientic development in the same domain. Furthermore, we disentangle between private companies and universities in order to assess whether patenting impacts differently on the two groups. In addition, we study to which extend the degree of applicability of an innovation is further affects the relation. To address these issues we build a novel dataset matching patent data (retrieved from USPTO) and publication data (retrieved from Thompson-Web of Science). Results show that patenting reduces the rate of citations of the paired publication indicating a decrease of related scientic activity only in case the citing agent belongs to a public institution. In addition, the the more invention is applied, the weaker is the negative effect. This paper makes a contribution to the debate on IPR and economics of science.

Suggested Citation

  • Arianna Martinelli & Elena Romito, 2019. "When authors become inventors: an empirical analysis on patent-paper pairs in medical research," LEM Papers Series 2019/32, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
  • Handle: RePEc:ssa:lemwps:2019/32
    as

    Download full text from publisher

    File URL: http://www.lem.sssup.it/WPLem/files/2019-32.pdf
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Philippe Aghion & Mathias Dewatripont & Julian Kolev & Fiona Murray & Scott Stern, 2016. "Of Mice and Academics: Examining the Effect of Openness on Innovation," PSE-Ecole d'économie de Paris (Postprint) halshs-01496928, HAL.
    2. Cameron,A. Colin & Trivedi,Pravin K., 2013. "Regression Analysis of Count Data," Cambridge Books, Cambridge University Press, number 9781107667273.
    3. Paulo Guimarães & Pedro Portugal, 2010. "A simple feasible procedure to fit models with high-dimensional fixed effects," Stata Journal, StataCorp LP, vol. 10(4), pages 628-649, December.
    4. Murray, Fiona, 2002. "Innovation as co-evolution of scientific and technological networks: exploring tissue engineering," Research Policy, Elsevier, vol. 31(8-9), pages 1389-1403, December.
    5. Fiona Murray & Philippe Aghion & Mathias Dewatripont & Julian Kolev & Scott Stern, 2016. "Of Mice and Academics: Examining the Effect of Openness on Innovation," American Economic Journal: Economic Policy, American Economic Association, vol. 8(1), pages 212-252, February.
    6. Reitzig, Markus & Henkel, Joachim & Heath, Christopher, 2007. "On sharks, trolls, and their patent prey--Unrealistic damage awards and firms' strategies of "being infringed"," Research Policy, Elsevier, vol. 36(1), pages 134-154, February.
    7. Thursby, Jerry G. & Thursby, Marie C., 2011. "Has the Bayh-Dole act compromised basic research?," Research Policy, Elsevier, vol. 40(8), pages 1077-1083, October.
    8. Danzon, Patricia M. & Nicholson, Sean (ed.), 2012. "The Oxford Handbook of the Economics of the Biopharmaceutical Industry," OUP Catalogue, Oxford University Press, number 9780199742998.
    9. Scott Stern, 2004. "Do Scientists Pay to Be Scientists?," Management Science, INFORMS, vol. 50(6), pages 835-853, June.
    10. Partha, Dasgupta & David, Paul A., 1994. "Toward a new economics of science," Research Policy, Elsevier, vol. 23(5), pages 487-521, September.
    11. Richard C. Levin & Alvin K. Klevorick & Richard R. Nelson & Sidney G. Winter, 1987. "Appropriating the Returns from Industrial Research and Development," Brookings Papers on Economic Activity, Economic Studies Program, The Brookings Institution, vol. 18(3, Specia), pages 783-832.
    12. Bhaven Sampat & Heidi L. Williams, 2019. "How Do Patents Affect Follow-On Innovation? Evidence from the Human Genome," American Economic Review, American Economic Association, vol. 109(1), pages 203-236, January.
    13. Mansfield, Edwin, 1998. "Academic research and industrial innovation: An update of empirical findings1," Research Policy, Elsevier, vol. 26(7-8), pages 773-776, April.
    14. Lokman I. Meho & Kiduk Yang, 2007. "Impact of data sources on citation counts and rankings of LIS faculty: Web of science versus scopus and google scholar," Journal of the American Society for Information Science and Technology, Association for Information Science & Technology, vol. 58(13), pages 2105-2125, November.
    15. Jeffrey L. Furman & Scott Stern, 2011. "Climbing atop the Shoulders of Giants: The Impact of Institutions on Cumulative Research," American Economic Review, American Economic Association, vol. 101(5), pages 1933-1963, August.
    16. Mazzoleni, Roberto & Nelson, Richard R., 1998. "The benefits and costs of strong patent protection: a contribution to the current debate," Research Policy, Elsevier, vol. 27(3), pages 273-284, July.
    17. Murray, Fiona & Stern, Scott, 2007. "Do formal intellectual property rights hinder the free flow of scientific knowledge?: An empirical test of the anti-commons hypothesis," Journal of Economic Behavior & Organization, Elsevier, vol. 63(4), pages 648-687, August.
    18. Fiona E. Murray & Scott Stern, 2007. "Do Formal Intellectual Property Rights Hinder the Free Flow of Scientific Knowledge?: An Empirical Test of the Anti-Commons Hypothesis," NBER Chapters, in: Academic Science and Entrepreneurship: Dual Engines of Growth, National Bureau of Economic Research, Inc.
    19. Gourieroux, Christian & Monfort, Alain & Trognon, Alain, 1984. "Pseudo Maximum Likelihood Methods: Applications to Poisson Models," Econometrica, Econometric Society, vol. 52(3), pages 701-720, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Gans, Joshua S. & Murray, Fiona E. & Stern, Scott, 2017. "Contracting over the disclosure of scientific knowledge: Intellectual property and academic publication," Research Policy, Elsevier, vol. 46(4), pages 820-835.
    2. Fehder, Daniel C. & Murray, Fiona & Stern, Scott, 2014. "Intellectual property rights and the evolution of scientific journals as knowledge platforms," International Journal of Industrial Organization, Elsevier, vol. 36(C), pages 83-94.
    3. Larsen, Maria Theresa, 2011. "The implications of academic enterprise for public science: An overview of the empirical evidence," Research Policy, Elsevier, vol. 40(1), pages 6-19, February.
    4. Choi, Jin-Uk & Lee, Chang-Yang, 2022. "The differential effects of basic research on firm R&D productivity: The conditioning role of technological diversification," Technovation, Elsevier, vol. 118(C).
    5. Boudreau, Kevin J. & Lakhani, Karim R., 2015. "“Open” disclosure of innovations, incentives and follow-on reuse: Theory on processes of cumulative innovation and a field experiment in computational biology," Research Policy, Elsevier, vol. 44(1), pages 4-19.
    6. Mueller-Langer, Frank & Fecher, Benedikt & Harhoff, Dietmar & Wagner, Gert G., 2019. "Replication studies in economics—How many and which papers are chosen for replication, and why?," Research Policy, Elsevier, vol. 48(1), pages 62-83.
    7. Jong, Simcha & Slavova, Kremena, 2014. "When publications lead to products: The open science conundrum in new product development," Research Policy, Elsevier, vol. 43(4), pages 645-654.
    8. Abhishek Nagaraj, 2018. "Does Copyright Affect Reuse? Evidence from Google Books and Wikipedia," Management Science, INFORMS, vol. 64(7), pages 3091-3107, July.
    9. Nelson, Andrew J., 2009. "Measuring knowledge spillovers: What patents, licenses and publications reveal about innovation diffusion," Research Policy, Elsevier, vol. 38(6), pages 994-1005, July.
    10. Simeth, Markus & Raffo, Julio D., 2013. "What makes companies pursue an Open Science strategy?," Research Policy, Elsevier, vol. 42(9), pages 1531-1543.
    11. Kwon, Seokbeom & Marco, Alan C., 2021. "Can antitrust law enforcement spur innovation? Antitrust regulation of patent consolidation and its impact on follow-on innovations," Research Policy, Elsevier, vol. 50(9).
    12. Hottenrott, Hanna & Lawson, Cornelia, 2017. "Fishing for complementarities: Research grants and research productivity," International Journal of Industrial Organization, Elsevier, vol. 51(C), pages 1-38.
    13. Florenta Teodoridis, 2018. "Understanding Team Knowledge Production: The Interrelated Roles of Technology and Expertise," Management Science, INFORMS, vol. 64(8), pages 3625-3648, August.
    14. Schaeffer, Véronique, 2019. "The use of material transfer agreements in academia: A threat to open science or a cooperation tool?," Research Policy, Elsevier, vol. 48(9), pages 1-1.
    15. Nancy Gallini, 2017. "Do patents work? Thickets, trolls and antibiotic resistance," Canadian Journal of Economics, Canadian Economics Association, vol. 50(4), pages 893-926, November.
    16. Wipo, 2011. "World Intellectual Property Report 2011- The Changing Face of Innovation," WIPO Economics & Statistics Series, World Intellectual Property Organization - Economics and Statistics Division, number 2011:944, April.
    17. Mark J. McCabe & Christopher M. Snyder, 2015. "Does Online Availability Increase Citations? Theory and Evidence from a Panel of Economics and Business Journals," The Review of Economics and Statistics, MIT Press, vol. 97(1), pages 144-165, March.
    18. Heidi L. Williams, 2016. "Intellectual Property Rights and Innovation: Evidence from Health Care Markets," Innovation Policy and the Economy, University of Chicago Press, vol. 16(1), pages 53-87.
    19. Mukherjee, Arijit & Stern, Scott, 2009. "Disclosure or secrecy? The dynamics of Open Science," International Journal of Industrial Organization, Elsevier, vol. 27(3), pages 449-462, May.
    20. Mueller-Langer, Frank & Scheufen, Marc & Waelbroeck, Patrick, 2020. "Does online access promote research in developing countries? Empirical evidence from article-level data," Research Policy, Elsevier, vol. 49(2).

    More about this item

    Keywords

    IPRs; Patent; Scientific publications; Applicability.;
    All these keywords.

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:ssa:lemwps:2019/32. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: the person in charge (email available below). General contact details of provider: https://edirc.repec.org/data/labssit.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.