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Non-standard bioinformatics analysis of SARS-CoV-2 virus

Author

Listed:
  • Dorota Bieli?ska-W??

    (Medical University of Gda?sk)

  • Piotr W??

    (Medical University of Gda?sk)

Abstract

A broad branch of bioinformatics are "alignment-free" computational methods combining ideas from various fields of science [1]. They often offer graphical and numerical tools for comparing biological sequences. The applications of alignment-free methods are wide. Each method reveals different aspects of sequence similarity. A variety of accurate approaches are of particular potential importance in medical sciences, for example in the bioinformatics characterization of viruses. In this work, we review the method we introduced, called 4D-Dynamic Representations of DNA/RNA Sequences [2,3]. This approach implements concepts and ideas originally developed in classical dynamics. The distribution of point clusters that appeared on our classification maps supports the hypothesis that SARS-CoV-2 virus could have originated from a bat and a pangolin [2].References:[1]. N. Ramanathan, J. Ramamurthy, G. Natarajan,Numerical Characterization of DNA Sequences for Alignment-free SequenceComparison - A Review, Combinatorial Chemistry & High Throughput Screening25 (2022), pp. 365-380.[2]. D. Bieli?ska-W??, P. W??, Non-standard bioinformaticscharacterization of SARS-CoV-2, Computers in Biology and Medicine 131 (2021)Art. No. 104247.[3]. D. Bieli?ska-W??, P. W??, A. Lass, J. Karamon, 4D-DynamicRepresentation of DNA/RNA Sequences: Studies on Genetic Diversity ofEchinococcus Multilocularis in Red Foxes in Poland, Life 12 (2022) Art.No. 877.

Suggested Citation

  • Dorota Bieli?ska-W?? & Piotr W??, 0000. "Non-standard bioinformatics analysis of SARS-CoV-2 virus," Proceedings of International Academic Conferences 14216136, International Institute of Social and Economic Sciences.
    • Handle: RePEc:sek:iacpro:14216136
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