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A new combination testing methodology to identify accurate and economical point-of-care testing strategies

Author

Listed:
  • Sanjay Jain
  • Jónas Oddur Jónasson
  • Jean Pauphilet
  • Barnaby Flower
  • Maya Moshe
  • Gianluca Fontana
  • Sutharsan Satkunarajah
  • Richard Tedder
  • Myra McClure
  • Hutan Ashrafian
  • Paul Elliott
  • Wendy S Barclay
  • Christina Atchison
  • Helen Ward
  • Graham Cooke
  • Ara Darzi
  • Kamalini Ramdas

Abstract

Current CDC guidelines suggest combining tests, noting that “performance of orthogonal testing algorithms has not been systematically evaluated” and highlighting discordant outcomes. Our methodology combines available LFIAs to meet desired accuracy criteria, by identifying testing possibility frontiers which encompass benchmarks, enabling cost savings. Our methodology applies equally to antigen testing and can greatly expand testing capacity through combining less accurate tests, especially for use cases needing quick, accurate tests, e.g., entry to public spaces such as airports, nursing homes or hospitals.

Suggested Citation

  • Sanjay Jain & Jónas Oddur Jónasson & Jean Pauphilet & Barnaby Flower & Maya Moshe & Gianluca Fontana & Sutharsan Satkunarajah & Richard Tedder & Myra McClure & Hutan Ashrafian & Paul Elliott & Wendy S, 2021. "A new combination testing methodology to identify accurate and economical point-of-care testing strategies," Economics Series Working Papers 958, University of Oxford, Department of Economics.
    • Handle: RePEc:oxf:wpaper:958
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    File URL: https://ora.ox.ac.uk/objects/uuid:4a71cc11-9332-4da9-8886-9f926a203e90
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    References listed on IDEAS

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    1. Giorgia Guglielmi, 2021. "Rapid coronavirus tests: a guide for the perplexed," Nature, Nature, vol. 590(7845), pages 202-205, February.
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