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Public Health Impact and Cost-Effectiveness of Empagliflozin (JARDIANCE®) in the Treatment of Patients with Heart Failure with Preserved Ejection Fraction in France, Based on the EMPEROR-Preserved Clinical Trial

Author

Listed:
  • Laurent Fauchier

    (CHRU Tours - Centre Hospitalier Régional Universitaire de Tours, EES - Éducation Éthique Santé EA 7505 - UT - Université de Tours)

  • Nicolas Lamblin

    (CHRU Lille - Centre Hospitalier Régional Universitaire [CHU Lille])

  • Jean Tardu

    (Creativ-Ceutical France - Creativ-Ceutical)

  • Lucile Bellier

    (Laboratoire d'Ethique Médicale, de Droit de la Santé et de Santé Publique - UPD5 - Université Paris Descartes - Paris 5)

  • Harinala Groyer

    (Boehringer Ingelheim)

  • Deborah Ittah

    (Boehringer Ingelheim)

  • Julien Chollet

    (Boehringer Ingelheim Pharma GmbH & Co. KG)

  • Stephan Linden

    (Boehringer Ingelheim)

  • Pierre Lévy

    (LEDa - Laboratoire d'Economie de Dauphine - IRD - Institut de Recherche pour le Développement - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres - CNRS - Centre National de la Recherche Scientifique, Legos - Laboratoire d'Economie et de Gestion des Organisations de Santé - Université Paris Dauphine-PSL - PSL - Université Paris Sciences et Lettres)

Abstract

Introduction: The efficacy and safety of empagliflozin in the treatment of heart failure with preserved ejection fraction (HFpEF) were demonstrated in the EMPEROR-Preserved trial, which showed a 21% reduction in combined risks of cardiovascular death or HF hospitalization [hazard ratio (HR) 0.79; 95% confidence interval (CI) 0.69–0.90, p

Suggested Citation

  • Laurent Fauchier & Nicolas Lamblin & Jean Tardu & Lucile Bellier & Harinala Groyer & Deborah Ittah & Julien Chollet & Stephan Linden & Pierre Lévy, 2023. "Public Health Impact and Cost-Effectiveness of Empagliflozin (JARDIANCE®) in the Treatment of Patients with Heart Failure with Preserved Ejection Fraction in France, Based on the EMPEROR-Preserved Cli," Post-Print hal-04439876, HAL.
    • Handle: RePEc:hal:journl:hal-04439876
    DOI: 10.1007/s41669-023-00432-z
    Note: View the original document on HAL open archive server: https://hal.science/hal-04439876v2
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    Keywords

    public health; heart failure; Clinical trial;
    All these keywords.

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