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Asthma burden according to treatment steps in the French population-based cohort CONSTANCES

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  • Nicolas Roche

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, Service de pneumologie [CHU Cochin] - Hôpital Cochin [AP-HP] - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP), IC UM3 (UMR 8104 / U1016) - Institut Cochin - INSERM - Institut National de la Santé et de la Recherche Médicale - CNRS - Centre National de la Recherche Scientifique - UPCité - Université Paris Cité)

  • Rachel Nadif

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay)

  • Caroline Fabry-Vendrand
  • Laura Pillot
  • Gabriel Thabut
  • Clément Teissier
  • Stéphane Bouée
  • Marcel Goldberg

    (CONSTANCES - Cohortes épidémiologiques en population - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay - UPCité - Université Paris Cité)

  • Marie Zins

    (CONSTANCES - Cohortes épidémiologiques en population - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay - UPCité - Université Paris Cité)

Abstract

Background: Data on health care consumption and costs of asthma in the French population are scarce. Objectives: The study objective was to describe the burden of asthma according to GINA treatment steps in the CONSTANCES cohort. Methods: Data from 162,725 participants included between 2012 and 2019 were extracted. Participants were considered as current asthmatics if asthma was reported at inclusion and asthma symptoms and/or treatments were reported in 2019. Participants were classified in three categories according to GINA treatment steps. The results were compared to non-asthmatic participants matched with a propensity score calculated on age, sex, region of residence, precariousness score and year of inclusion. Results: Among 162,725 participants aged 18–69 years, 6783 asthmatics (1566 not treated for asthma, 2444 + 251 GINA steps 1 + 2, 1054 + 1315 GINA steps 3 + 4, and 153 GINA step 5) were matched with 6783 controls. Average annual ambulatory cost and average annual hospitalization cost were respectively €1925 and €719 for asthmatics versus €1376 and €511 for participants without asthma (p

Suggested Citation

  • Nicolas Roche & Rachel Nadif & Caroline Fabry-Vendrand & Laura Pillot & Gabriel Thabut & Clément Teissier & Stéphane Bouée & Marcel Goldberg & Marie Zins, 2023. "Asthma burden according to treatment steps in the French population-based cohort CONSTANCES," Post-Print hal-03949592, HAL.
    • Handle: RePEc:hal:journl:hal-03949592
    DOI: 10.1016/j.rmed.2022.107057
    Note: View the original document on HAL open archive server: https://hal.science/hal-03949592
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    References listed on IDEAS

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    1. Christian Jacob & Benno Bechtel & Susanne Engel & Peter Kardos & Roland Linder & Sebastian Braun & Wolfgang Greiner, 2016. "Healthcare costs and resource utilization of asthma in Germany: a claims data analysis," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 17(2), pages 195-201, March.
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      Keywords

      Asthma; Burden of disease; CONSTANCES; Economic evaluation; France; GINA; SNDS; Treatment steps;
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