IDEAS home Printed from https://ideas.repec.org/p/hal/journl/hal-03930527.html
   My bibliography  Save this paper

The effect of the 7R allele on the DRD4 risk tolerance locus is independent of background risk in Senegalese fishermen

Author

Listed:
  • Gwen-Jiro Clochard

    (CREST - Centre de Recherche en Économie et Statistique - ENSAI - Ecole Nationale de la Statistique et de l'Analyse de l'Information [Bruz] - X - École polytechnique - IP Paris - Institut Polytechnique de Paris - ENSAE Paris - École Nationale de la Statistique et de l'Administration Économique - CNRS - Centre National de la Recherche Scientifique)

  • Aby Mbengue

    (UGB - Université Gaston Berger de Saint-Louis Sénégal)

  • Clément Mettling

    (IGH - Institut de génétique humaine - CNRS - Centre National de la Recherche Scientifique - UM - Université de Montpellier)

  • Birane Diouf

    (UGB - Université Gaston Berger de Saint-Louis Sénégal)

  • Charlotte Faurie

    (UMR ISEM - Institut des Sciences de l'Evolution de Montpellier - Cirad - Centre de Coopération Internationale en Recherche Agronomique pour le Développement - EPHE - École Pratique des Hautes Études - PSL - Université Paris Sciences et Lettres - Institut de recherche pour le développement [IRD] : UR226 - CNRS - Centre National de la Recherche Scientifique - UM - Université de Montpellier)

  • Omar Sene

    (UADB - Université Alioune Diop de Bambey)

  • Emilie Chancerel

    (BioGeCo - Biodiversité, Gènes & Communautés - UB - Université de Bordeaux - INRAE - Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement)

  • Erwan Guichoux

    (BioGeCo - Biodiversité, Gènes & Communautés - UB - Université de Bordeaux - INRAE - Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement)

  • Guillaume Hollard

    (X - École polytechnique - IP Paris - Institut Polytechnique de Paris)

  • Michel Raymond

    (UMR ISEM - Institut des Sciences de l'Evolution de Montpellier - Cirad - Centre de Coopération Internationale en Recherche Agronomique pour le Développement - EPHE - École Pratique des Hautes Études - PSL - Université Paris Sciences et Lettres - Institut de recherche pour le développement [IRD] : UR226 - CNRS - Centre National de la Recherche Scientifique - UM - Université de Montpellier)

  • Marc Willinger

    (CEE-M - Centre d'Economie de l'Environnement - Montpellier - CNRS - Centre National de la Recherche Scientifique - INRAE - Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement - Institut Agro Montpellier - Institut Agro - Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement - UM - Université de Montpellier)

Abstract

It has been shown that living in risky environments, as well as having a risky occupation, can moderate risk-tolerance. Despitethe involvement of dopamine in the expectation of reward described by neurobiologists, a GWAS study was not able todemonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studiesgave contrasting results. We test the possibility that a genetic effect of the DRD4-7R allele in risk-taking behavior could bemodulated by environmental factors. We show that the increase in risk-tolerance due to the 7R allele is independent of theenvironmental risk in two populations in Northern Senegal, one of which is exposed to a very high risk due to dangerous fishing.

Suggested Citation

  • Gwen-Jiro Clochard & Aby Mbengue & Clément Mettling & Birane Diouf & Charlotte Faurie & Omar Sene & Emilie Chancerel & Erwan Guichoux & Guillaume Hollard & Michel Raymond & Marc Willinger, 2023. "The effect of the 7R allele on the DRD4 risk tolerance locus is independent of background risk in Senegalese fishermen," Post-Print hal-03930527, HAL.
    • Handle: RePEc:hal:journl:hal-03930527
    DOI: 10.21203/rs.3.rs-1968350/v1
    Note: View the original document on HAL open archive server: https://hal.inrae.fr/hal-03930527
    as

    Download full text from publisher

    File URL: https://hal.inrae.fr/hal-03930527/document
    Download Restriction: no
    File URL: https://libkey.io/10.21203/rs.3.rs-1968350/v1?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:hal:journl:hal-03930527. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: CCSD (email available below). General contact details of provider: https://hal.archives-ouvertes.fr/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.