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The Ambulatory Medical Assistance (AMA) programme during active‐phase treatment in patients with haematological malignancies: A cost‐effectiveness analysis

Author

Listed:
  • Anne‐sophie Michallet
  • Stephanie Malartre
  • Elodie Vignaud
  • Alexiane Bocquet
  • Pascale Sontag
  • Christelle Galvez
  • Jean‐yves Blay
  • Pierre Heudel
  • Alexandre Vimont
  • Martin Blachier
  • Marie Ferrua
  • Olivier Mir
  • Etienne Minvielle

    (i3-CRG - Centre de recherche en gestion i3 - X - École polytechnique - IP Paris - Institut Polytechnique de Paris - Université Paris-Saclay - I3 - Institut interdisciplinaire de l’innovation - CNRS - Centre National de la Recherche Scientifique)

Abstract

Context: The need for patient navigator is growing, and there is a lack of cost evaluation, especially during survivorship. Objective: The objective of this study is to evaluate the cost-effectiveness of an Ambulatory Medical Assistance (AMA) programme in patients with haematological malignancies (HM). Design: A cost-effectiveness analysis of the AMA programme was performed compared to a simulated control arm. Setting: An interventional, single-arm and prospective study was conducted in a French reference haematology–oncology centre between 2016 and 2020. Participants: Adult patients were enrolled with histologically documented malignant haematology, during their active therapy phase, and treated either by intravenous chemotherapy or oral therapy. Methods: An extrapolation of the effectiveness was derived from a similar nurse monitoring programme (CAPRI study). Cost effectiveness of the programme was evaluated through adverse events of Grade 3 or 4 avoided in different populations. Results: Included patient (n=797) from the AMA programme were followed during125 days (IQR: 0–181), and adverse events (Grade 3/4) were observed in 10.1% of patients versus 13.4% in the simulated control arm. The overall cost of AE avoided was estimated to€81,113, leading to an ICER of€864. Conclusion: The AMA programme was shown to be cost-effective compared to a simulated control arm with no intervention

Suggested Citation

  • Anne‐sophie Michallet & Stephanie Malartre & Elodie Vignaud & Alexiane Bocquet & Pascale Sontag & Christelle Galvez & Jean‐yves Blay & Pierre Heudel & Alexandre Vimont & Martin Blachier & Marie Ferrua, 2022. "The Ambulatory Medical Assistance (AMA) programme during active‐phase treatment in patients with haematological malignancies: A cost‐effectiveness analysis," Post-Print hal-03889400, HAL.
    • Handle: RePEc:hal:journl:hal-03889400
    DOI: 10.1111/ecc.13709
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