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Cost-effectiveness analysis of thermotherapy versus pentava-lent antimonials for the treatment of cutaneous leishmaniasis

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  • Mery Patricia Tamayo
  • Jaiberth Antonio Cardona-Arias
  • Liliana López Carvajal
  • Iván Darío Vélez

Abstract

Introduction: The treatment of cutaneous leishmaniasis is toxic, has contraindications and a high cost. Objective: To estimate the cost-effectiveness of thermotherapy versus pentavalent antimonials for the treatment of cutaneous leishmaniasis. Methods: Effectiveness was the proportion of healing, and safety with the adverse effects; these parameters were estimated from a controlled clinical trial and a meta-analysis. A standard costing were conducted. Average and incremental cost-effectiveness ratios were estimated. The uncertainty regarding effectiveness, safety and costs was determined through sensitivity analyses. Results: The total costs were $66,807 with Glucantime and $14,079 with thermotherapy. The therapeutic effectiveness rates were 64.2% for thermotherapy and 85.1% for Glucantime. The average cost-effectiveness ratios ranged between $721 and $1,275 for Glucantime and between $187 and $390 for thermotherapy. Based on the meta-analysis thermotherapy may be a dominant strategy. Conclusion: The excellent cost-effectiveness ratio of thermotherapy shows the relevance of its inclusion in guidelines for the treatment.

Suggested Citation

  • Mery Patricia Tamayo & Jaiberth Antonio Cardona-Arias & Liliana López Carvajal & Iván Darío Vélez, 2018. "Cost-effectiveness analysis of thermotherapy versus pentava-lent antimonials for the treatment of cutaneous leishmaniasis," Documentos de Trabajo de Valor Público 16361, Universidad EAFIT.
    • Handle: RePEc:col:000122:016361
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    File URL: https://repository.eafit.edu.co/handle/10784/12419
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    Keywords

    Cost-Effectiveness AnalysisCutaneous LeishmaniasisThermotherapyAntimony Sodium GluconateColombia;

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