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Adjusting for cross-over in a trial with survival end-points

Author

Listed:
  • Ian White

    (BSU, Cambridge)

  • Abdel Babiker

    (University College London)

  • Sarah Walker

    (University College London)

Abstract

We consider a two-group clinical trial with a survival outcome, in which some subjects may 'cross over' to receive the treatment of the other arm. Our command strbee adjusts for treatment cross-over in one or both arms. This is done by a randomization-respecting method which preserves the intention-to-treat P-value.

Suggested Citation

  • Ian White & Abdel Babiker & Sarah Walker, 2001. "Adjusting for cross-over in a trial with survival end-points," United Kingdom Stata Users' Group Meetings 2001 3, Stata Users Group.
    • Handle: RePEc:boc:usug01:3
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