IDEAS home Printed from https://ideas.repec.org/p/boc/lsug24/15.html
   My bibliography  Save this paper

Visualisations to evaluate and communicate adverse event data in randomised controlled trials

Author

Listed:
  • Rachel Phillips

    (Imperial College London)

Abstract

Introduction: Well-designed visualisations are a powerful way to communicate information to a range of audiences. In randomised controlled trials (RCT) where there is an abundance of complex data on harms (known as adverse events) visualisations can be a highly effective means to summarise harm profiles and identify potential adverse reactions. Trial reporting guidelines such as the CONSORT extension for harms encourage the use of visualisations for exploring harm outcomes, but research has demonstrated that their uptake is extremely low. Methods: To improve the communication of adverse event data collected in RCTs we developed recommendations to help trialists decide which visualisations to use to present this data. We developed Stata commands (aedot and aevolcano) to produce two of the visualisations, the volcano and dot plot, to present adverse event data with the aim of easing implementation and promoting increased uptake. Results: In this talk, using clinical examples, we will introduce and demonstrate application of these commands. We will contrast the produced visual summaries from the volcano and dot plot with traditional non-graphical presentations of adverse data with examples in the published literature, with the aim of demonstrating the benefits of graphical displays. Discussion: Visualisations offer an efficient means to summarise large amounts of adverse event data from RCTs and statistical software eases the implementation of such displays. We hope that development of bespoke Stata commands to create visual summaries of adverse events will increase uptake of visualisations in this area by the applied clinical trial statistician.

Suggested Citation

  • Rachel Phillips, 2024. "Visualisations to evaluate and communicate adverse event data in randomised controlled trials," UK Stata Conference 2024 15, Stata Users Group.
  • Handle: RePEc:boc:lsug24:15
    as

    Download full text from publisher

    File URL: http://repec.org/lsug2024/UK24_Phillips.pptx
    Download Restriction: no
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:boc:lsug24:15. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://edirc.repec.org/data/stataea.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.