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A Genetic Classifier Account for the Regulation of Expression

In: Computational Neuroscience

Author

Listed:
  • Tsvi Achler

    (University of Illinois Urbana-Champaign)

  • Eyal Amir

    (University of Illinois Urbana-Champaign)

Abstract

This work is motivated by our model of neuroscience processing which incorporates large numbers of reentrant top-down feedback regulation connections. Such regulation is fundamental and can be found throughout biology. The purpose of this chapter is to broaden this model's application. Genes perform important life functions, responsible for virtually every organic molecule that organisms produce. The genes must closely regulate the amount of their products, because too little or too much production may be deleterious for the organism. Furthermore, they must respond efficiently and in unison to the environments that the organism faces. Networks that are closely regulated can behave as robust classifiers which can recognize and respond to their environment. Using simple examples we demonstrate that such networks perform dynamic classification, determining the most efficient set of genes needed to replace consumed products.

Suggested Citation

  • Tsvi Achler & Eyal Amir, 2010. "A Genetic Classifier Account for the Regulation of Expression," Springer Optimization and Its Applications, in: Wanpracha Chaovalitwongse & Panos M. Pardalos & Petros Xanthopoulos (ed.), Computational Neuroscience, chapter 0, pages 113-123, Springer.
  • Handle: RePEc:spr:spochp:978-0-387-88630-5_7
    DOI: 10.1007/978-0-387-88630-5_7
    as

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