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Investigating Functional Cooperation in the Human Brain Using Simple Graph-Theoretic Methods

In: Computational Neuroscience

Author

Listed:
  • Michael L. Anderson

    (Franklin and Marshall College
    University of Maryland)

  • Joan Brumbaugh

    (Franklin and Marshall College)

  • Aysu Şuben

    (Franklin and Marshall College)

Abstract

This chapter introduces a very simple analytic method for mining large numbers of brain imaging experiments to discover functional cooperation between regions. We then report some preliminary results of its application, illustrate some of the many future projects in which we expect the technique will be of considerable use (including a way to relate fMRI to EEG), and describe a research resource for investigating functional cooperation in the cortex that will be made publicly available through the lab web site. One significant finding is that differences between cognitive domains appear to be attributable more to differences in patterns of cooperation between brain regions, rather than to differences in which brain regions are used in each domain. This is not a result that is predicted by prevailing localization-based and modular accounts of the organization of the cortex.

Suggested Citation

  • Michael L. Anderson & Joan Brumbaugh & Aysu Şuben, 2010. "Investigating Functional Cooperation in the Human Brain Using Simple Graph-Theoretic Methods," Springer Optimization and Its Applications, in: Wanpracha Chaovalitwongse & Panos M. Pardalos & Petros Xanthopoulos (ed.), Computational Neuroscience, chapter 0, pages 31-42, Springer.
  • Handle: RePEc:spr:spochp:978-0-387-88630-5_2
    DOI: 10.1007/978-0-387-88630-5_2
    as

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