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Improvement of the Manufacturing Process of Active Pharmaceutical Ingredients

In: Driving Quality Management and Sustainability in VUCA Environments

Author

Listed:
  • A. C. P. Soares

    (ISEP—School of Engineering, Polytechnic of Porto, R. Dr. António Bernardino de Almeida)

  • R. D. S. Campilho

    (ISEP—School of Engineering, Polytechnic of Porto, R. Dr. António Bernardino de Almeida
    INEGI—Institute of Science and Innovation in Mechanical and Industrial Engineering, Pólo FEUP)

Abstract

Currently, the pharmaceutical industry needs to optimize industrial drug processing procedures. The constant improvement of industrial equipment is an unavoidable strategy to improve the quality of the process, as well as its efficiency and productivity. This work aims to analyze and implement improvements in equipment integrated into production processes in pharmaceutical laboratories to produce active pharmaceutical ingredients (APIs). In the project, studies were carried out using the finite element method (FEM) and traditional structural design, to test the feasibility of the selected solutions. Then, the cost analysis was carried out, and the benefits and results of the new equipment were presented. It was possible to conclude that the proposed equipment demonstrates advantages at an ergonomic, hygienic, and practical level compared to the original ones, which translates into an increase of the company’s competitiveness in the pharmaceutical market.

Suggested Citation

  • A. C. P. Soares & R. D. S. Campilho, 2024. "Improvement of the Manufacturing Process of Active Pharmaceutical Ingredients," Springer Proceedings in Business and Economics, in: João Reis & Tiago Pinho & Vítor Barbosa & Luís Barreto & Sandrina B. Moreira & Pedro Pardal & João N (ed.), Driving Quality Management and Sustainability in VUCA Environments, pages 15-28, Springer.
    • Handle: RePEc:spr:prbchp:978-3-031-52723-4_2
    DOI: 10.1007/978-3-031-52723-4_2
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