IDEAS home Printed from https://ideas.repec.org/h/ito/pchaps/212731.html
   My bibliography  Save this book chapter

Zinc in Human Health

In: Personalized Medicine, in Relation to Redox State, Diet and Lifestyle

Author

Listed:
  • Ananda S. Prasad

Abstract

The essential role of zinc in human health was first suggested by our studies in growth-retarded Iranian villagers in 1961. Our later studies in 1963 established conclusively that zinc was essential for human and that zinc deficiency resulted in severe growth retardation, hypogonadism in males, immune dysfunctions, and cognitive function impairment. The suggestion that zinc was an essential element for humans remained very controversial, but in 1974, the USA National Academy of Sciences declared zinc as an essential element for humans and established the recommended dietary allowances. In 1978, the FDA and other regulatory agencies made it mandatory to include zinc in total parenteral nutrition fluids, which resulted in saving many lives. During the past five decades, tremendous progress has been made in the understanding of the biochemical role of zinc, and we now know that zinc therapy has impacted significantly on human health and diseases. In this review, I plan to present a brief historical review of the discovery of zinc as an essential element for humans, the clinical manifestations of zinc deficiency, its therapeutic impact on human health and diseases, biomarkers of human zinc deficiency, and its biochemical role.

Suggested Citation

  • Ananda S. Prasad, 2020. "Zinc in Human Health," Chapters, in: Faik Atroshi (ed.), Personalized Medicine, in Relation to Redox State, Diet and Lifestyle, IntechOpen.
    • Handle: RePEc:ito:pchaps:212731
    DOI: 10.5772/intechopen.92005
    as

    Download full text from publisher

    File URL: https://www.intechopen.com/chapters/71772
    Download Restriction: no
    File URL: https://libkey.io/10.5772/intechopen.92005?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ng, Kok Siew & Head, Ian & Premier, Giuliano C. & Scott, Keith & Yu, Eileen & Lloyd, Jon & Sadhukhan, Jhuma, 2016. "A multilevel sustainability analysis of zinc recovery from wastes," Resources, Conservation & Recycling, Elsevier, vol. 113(C), pages 88-105.
    2. Wenyan Xie & Qinghua Xue & Liangfei Niu & Ka-Wing Wong, 2020. "Zinc transporter SLC39A7 relieves zinc deficiency to suppress alternative macrophage activation and impairment of phagocytosis," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-12, July.
    3. Shamaraz Firdous & Amanat Ali & Shahzad Anwar, 2018. "Optical Polarimatic Characterization of Zinc Oxide Nanorods as a Photosensitizer for Photodynamic Therapy," Cancer Therapy & Oncology International Journal, Juniper Publishers Inc., vol. 11(1), pages 1-7, May.

    More about this item

    Keywords

    zinc; anti-inflammatory agent; antioxidant agent; oxidative stress; inflammatory cytokines;
    All these keywords.

    JEL classification:

    • I11 - Health, Education, and Welfare - - Health - - - Analysis of Health Care Markets

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:ito:pchaps:212731. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Slobodan Momcilovic (email available below). General contact details of provider: http://www.intechopen.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.