Impacts of sac centreline length on hemodynamic of Anterior Cerebral Artery for rupture risk analysis via computational study

Intracranial aneurysms (IAs) are focal dilations of the cerebral arteries that pose a significant risk of rupture, leading to potentially devastating consequences such as subarachnoid hemorrhage. Understanding the hemodynamic factors that contribute to IA rupture risk is critical for improving clinical management and patient outcomes. One important factor that has been studied is the impact of sac centreline length on the hemodynamics of the Anterior Cerebral Artery (ACA), a common location for IAs. This computational study aimed to investigate the relationship between sac centreline length and the hemodynamic parameters of the ACA that are associated with rupture risk. Using patient-specific 3D geometries of the ACA and computational fluid dynamics (CFD) simulations, the researchers analyzed the impact of varying sac centreline lengths on parameters such as wall shear stress, pressure and flow patterns within the aneurysm sac and the parent artery. The results of the computational study disclose that the wall shear stress on the wall of an ACA saccular aneurysm is meaningfully high when the size of the sac centerline length is low. However, the mean oscillatory index change in different sac centerline lengths indicates that the growth of sac centerline length increases blood oscillatory in sac section in ACA cases.