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Ambiguous Carcinogens and Their Regulation

Author

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  • Alvin M. Weinberg
  • John B. Storer

Abstract

Examination of five animal and one human studies suggest that certain agents increase the incidence of some cancers but simultaneously reduce the incidence of other cancers. Yellow die 3, for example, sharply increases the incidence of liver tumors but practically eliminates naturally occurring leukemia/lymphoma in F‐344 male rates. Such ambiguity in the action of presumed carcinogens suggests that caution must be used by regulatory bodies in proscribing suspected carcinogens, or even in recommending changes in lifestyle or dietary habits as a means of reducing incidence of cancer.

Suggested Citation

  • Alvin M. Weinberg & John B. Storer, 1985. "Ambiguous Carcinogens and Their Regulation," Risk Analysis, John Wiley & Sons, vol. 5(2), pages 151-156, June.
    • Handle: RePEc:wly:riskan:v:5:y:1985:i:2:p:151-156
    DOI: 10.1111/j.1539-6924.1985.tb00162.x
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    Cited by:

    1. J. K. Haseman, 1985. "Evaluating the Carcinogenic Potential of a Chemical That Appears to Both Increase and Decrease Tumor Incidences," Risk Analysis, John Wiley & Sons, vol. 5(2), pages 161-164, June.

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