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Scenario‐Based Risk Assessment of Multi‐Use Chemicals: Application to Solvents

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  • Martin Scheringer
  • Thomas Vögl
  • Julia Von Grote
  • Béatrice Capaul
  • Renate Schubert
  • Konrad Hungerbühler

Abstract

The risk through chemical exposure is commonly characterized by ratios of exposure concentrations and effect levels (risk quotients). For chemicals with many different applications such as solvents, however, in addition to the risk quotients of different exposure situations it is useful to determine the corresponding numbers of exposed individuals, that is, not only the magnitude but also the extent of the risk. To this end, the Scenario‐Based Risk Assessment (SceBRA) method has been developed that makes use of a large set of scenarios, each of which describes a typical situation regarding handling a solvent or solvent‐containing product. The scenarios cover the life‐cycle steps of production, distribution, and use of solvents. For each scenario, SceBRA provides the risk quotient, r, and the number of exposed individuals, N. This study investigated seven solvents that are used in large amounts in Switzerland. For each solvent, characteristic distributions of r and N values were calculated, making it possible to compare different solvents with respect to their risk profile. Graphical representations of the r, N data provide an informative way for analyzing and communicating the results of SceBRA.

Suggested Citation

  • Martin Scheringer & Thomas Vögl & Julia Von Grote & Béatrice Capaul & Renate Schubert & Konrad Hungerbühler, 2001. "Scenario‐Based Risk Assessment of Multi‐Use Chemicals: Application to Solvents," Risk Analysis, John Wiley & Sons, vol. 21(3), pages 481-498, June.
    • Handle: RePEc:wly:riskan:v:21:y:2001:i:3:p:481-498
    DOI: 10.1111/0272-4332.213127
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    Cited by:

    1. Matthias Wormuth & Martin Scheringer & Meret Vollenweider & Konrad Hungerbühler, 2006. "What Are the Sources of Exposure to Eight Frequently Used Phthalic Acid Esters in Europeans?," Risk Analysis, John Wiley & Sons, vol. 26(3), pages 803-824, June.
    2. Matthias Wormuth & Evangelia Demou & Martin Scheringer & Konrad Hungerbühler, 2007. "Assessments of Direct Human Exposure—The Approach of EU Risk Assessments Compared to Scenario‐Based Risk Assessment," Risk Analysis, John Wiley & Sons, vol. 27(4), pages 979-990, August.

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