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Distribution of Exposure Concentrations and Doses for Constituents of Environmental Tobacco Smoke

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  • Judy S. LaKind
  • Michael E. Ginevan
  • Daniel Q. Naiman
  • Anthony C. James
  • Roger A. Jenkins
  • Michael L. Dourson
  • Susan P. Felter
  • Carol G. Graves
  • Robert G. Tardiff

Abstract

The ultimate goal of the research reported in this series of three articles is to derive distributions of doses of selected environmental tobacco smoke (ETS)‐related chemicals for nonsmoking workers. This analysis uses data from the 16‐City Study collected with personal monitors over the course of one workday in workplaces where smoking occurred. In this article, we describe distributions of ETS chemical concentrations and the characteristicsof those distributions (e.g., whether the distribution was log normal for agiven constituent) for the workplace exposure. Next, we present population parameters relevant for estimating dose distributions and the methods used for estimating those dose distributions. Finally, we derive distributions of doses of selected ETS‐related constituents obtained in the workplace for people in smoking work environments. Estimating dose distributions providedinformation beyond the usual point estimate of dose and showed that the preponderance of individuals exposed to ETS in the workplace were exposed at the low end of the dose distribution curve. The results of this analysis include estimations of hourly maxima and time‐weighted average (TWA) doses of nicotine from workplace exposures to ETS (extrapolated from 1 day to 1 week) and doses derived from modeled lung burdens of ultraviolet‐absorbing particulate matter (UVPM) and solanesol resulting from workplace exposures to ETS (extrapolated from 1 day to 1 year).

Suggested Citation

  • Judy S. LaKind & Michael E. Ginevan & Daniel Q. Naiman & Anthony C. James & Roger A. Jenkins & Michael L. Dourson & Susan P. Felter & Carol G. Graves & Robert G. Tardiff, 1999. "Distribution of Exposure Concentrations and Doses for Constituents of Environmental Tobacco Smoke," Risk Analysis, John Wiley & Sons, vol. 19(3), pages 375-390, June.
    • Handle: RePEc:wly:riskan:v:19:y:1999:i:3:p:375-390
    DOI: 10.1111/j.1539-6924.1999.tb00414.x
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    References listed on IDEAS

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    1. Jennifer Brainard & David E. Burmaster, 1992. "Bivariate Distributions for Height and Weight of Men and Women in the United States," Risk Analysis, John Wiley & Sons, vol. 12(2), pages 267-275, June.
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    Cited by:

    1. Richard A. Forshee & Maureen L. Storey & Michael E. Ginevan, 2005. "A Risk Analysis Model of the Relationship Between Beverage Consumption from School Vending Machines and Risk of Adolescent Overweight," Risk Analysis, John Wiley & Sons, vol. 25(5), pages 1121-1135, October.

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