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Association of cardiovascular emerging risk factors with acute coronary syndrome and stroke: A case‐control study

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  • José Manuel Martínez Linares
  • Rafael Guisado Barrilao
  • Francisco Manuel Ocaña Peinado
  • Francisco Javier Salgado Parreño

Abstract

In this study, we estimated the risk of acute coronary syndrome and stroke associated with several emerging cardiovascular risk factors. This was a case‐control study, where an age ‐ and sex‐matched acute coronary syndrome group and stroke group were compared with controls. Demographic and clinical data were collected through patient interviews, and blood samples were taken for analysis. In the bivariate analysis, all cardiovascular risk factors analyzed showed as predictors of acute coronary syndrome and stroke, except total cholesterol and smoking. In the multivariate logistic regression model for acute coronary syndrome, hypertension and body mass index, N‐terminal section brain natriuretic peptide and pregnancy‐associated plasma protein‐A were independent predictors. For stroke, the predictors were hypertension, diabetes mellitus, body mass index, and N‐terminal section brain natriuretic peptide. Controlling for age, sex, and classical cardiovascular risk factors, N‐terminal section brain natriuretic peptide and pregnancy‐associated plasma protein‐A were independent emerging cardiovascular risk factors for acute coronary syndrome, but pregnancy‐associated plasma protein‐A was not for stroke. High levels of cardiovascular risk factors in individuals with no episodes of cardiovascular disease requires the implementation of prevention programs, given that at least half of them are modifiable.

Suggested Citation

  • José Manuel Martínez Linares & Rafael Guisado Barrilao & Francisco Manuel Ocaña Peinado & Francisco Javier Salgado Parreño, 2016. "Association of cardiovascular emerging risk factors with acute coronary syndrome and stroke: A case‐control study," Nursing & Health Sciences, John Wiley & Sons, vol. 18(4), pages 488-495, December.
  • Handle: RePEc:wly:nuhsci:v:18:y:2016:i:4:p:488-495
    DOI: 10.1111/nhs.12299
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    Cited by:

    1. Hye Yon Yu & Eun Kyoung Ahn & Eun Ji Seo, 2019. "Relationship between the frequency of nursing activities and adverse outcomes in patients with acute coronary syndrome: A retrospective cohort study," Nursing & Health Sciences, John Wiley & Sons, vol. 21(4), pages 531-537, December.
    2. Ping‐ping He & Qian‐qian Shen & Ye‐shi Chen & Juping Yu & Zhao‐xia Li & Xin‐ping Ouyang, 2020. "Development and validation of a Chinese‐language instrument measuring empowerment needs of patients after a percutaneous coronary intervention," Nursing & Health Sciences, John Wiley & Sons, vol. 22(2), pages 364-373, June.

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