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The Interplay between Maternal Smoking and Genes in Offspring Birth Weight

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Listed:
  • Rita Dias Pereira
  • Cornelius A. Rietveld
  • Hans van Kippersluis

Abstract

It is well established that birth weight is affected by the child’s genetic endowments and maternal smoking during pregnancy. Here, we investigate whether an interaction between genetic endowments and maternal smoking on birth weight exists. We instrument the maternal smoking decision with a genetic variant (rs1051730) located in the nicotine receptor gene CHRNA3 and deal with the underreporting of maternal smoking by using a biomarker of nicotine collected during pregnancy. We confirm that genetic endowments and maternal smoking negatively affect the child’s birth weight. However, we do not find evidence of meaningful interactions between genetic endowments and maternal smoking.

Suggested Citation

  • Rita Dias Pereira & Cornelius A. Rietveld & Hans van Kippersluis, 2025. "The Interplay between Maternal Smoking and Genes in Offspring Birth Weight," Journal of Human Resources, University of Wisconsin Press, vol. 60(2), pages 400-433.
    • Handle: RePEc:uwp:jhriss:v:60:y:2025:i:2:p:400-433
    Note: DOI: https://doi.org/10.3368/jhr.1020-11266R2
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    File URL: http://jhr.uwpress.org/cgi/reprint/60/2/400
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    More about this item

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General
    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality

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