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Exploratory analysis of single nucleotide polymorphism (SNP) for quantitative traits

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  • Mario A. Cleves

    (UAMS College of Medicine, Department of Pediatrics)

Abstract

With the decreasing cost and the increasing ability to quickly genotype single nucleotide polymorphisms (SNP) across the human genome, large databases containing possibly hundreds of typed SNPs are becoming common in populationbased studies of quantitative traits. Testing for association between individual SNPs and the quantitative trait is an important first step in the discovery of disease susceptibility SNPs. This task, however, could be time-consuming and tediousifalargenumberofSNPs is involved. In this article, I introduce two new commands designed to facilitate the screening and testing of multiple SNPsfor possible association with quantitative traits. Copyright 2005 by StataCorp LP.

Suggested Citation

  • Mario A. Cleves, 2005. "Exploratory analysis of single nucleotide polymorphism (SNP) for quantitative traits," Stata Journal, StataCorp LP, vol. 5(2), pages 141-153, June.
    • Handle: RePEc:tsj:stataj:v:5:y:2005:i:2:p:141-153
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    References listed on IDEAS

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    1. Mario Cleves, 1999. "Hardy-Weinberg equilibrium test and allele frequency estimation," Stata Technical Bulletin, StataCorp LP, vol. 8(48).
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    Cited by:

    1. Yulia V. Marchenko & Raymond K. Carroll & Danyu Y. Lin & Christopher I. Amos & Roberto G. Gutierrez, 2008. "Semiparametric analysis of case–control genetic data in the presence of environmental factors," Stata Journal, StataCorp LP, vol. 8(3), pages 305-333, September.

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