IDEAS home Printed from https://ideas.repec.org/a/taf/nmcmxx/v9y2003i4p367-386.html
   My bibliography  Save this article

Development of a Cerebral Autoregulation Model for Use With Clinical Blood Flow Measurements

Author

Listed:
  • D. Schley
  • R.E. Craine
  • A.A. Birch

Abstract

Cerebral autoregulation is the mechanism which controls blood flow to the brain despite variations in blood pressure. Although important this mechanism is currently not well understood, with autoregulatory failure difficult to diagnose. In this paper we develop a simple model based upon those measurements available in the clinical setting. The model can replicate previous results and is used to investigate a variety of hypothetical autoregulatory responses. Furthermore the model has been extended by including the autoregulatory vessels themselves to explain the observed influence of increased carbon dioxide levels in the blood. A focus on only those measurements which may be realistically obtained in human patients avoids the need for estimating many unknown parameters or the modelling of complex and poorly understood physiological process necessary in previous, more complicated, models.

Suggested Citation

  • D. Schley & R.E. Craine & A.A. Birch, 2003. "Development of a Cerebral Autoregulation Model for Use With Clinical Blood Flow Measurements," Mathematical and Computer Modelling of Dynamical Systems, Taylor & Francis Journals, vol. 9(4), pages 367-386, December.
    • Handle: RePEc:taf:nmcmxx:v:9:y:2003:i:4:p:367-386
    DOI: 10.1076/mcmd.9.4.367.27901
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1076/mcmd.9.4.367.27901
    Download Restriction: Access to full text is restricted to subscribers.
    File URL: https://libkey.io/10.1076/mcmd.9.4.367.27901?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:taf:nmcmxx:v:9:y:2003:i:4:p:367-386. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Chris Longhurst (email available below). General contact details of provider: http://www.tandfonline.com/NMCM20 .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.