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Stochastic Modelling of Multiple Random Genetic Mutations Under the Cancer Stem Cell Hypothesis

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  • CRISTIAN TOMASETTI

Abstract

The probability distribution for the size of each of the various cancer cell subpopulations created by random genetic mutations is expressed in the case of non-exponential growth of cancer and in the case of a heterogeneous tumor cell population.

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  • Cristian Tomasetti, 2012. "Stochastic Modelling of Multiple Random Genetic Mutations Under the Cancer Stem Cell Hypothesis," Mathematical Population Studies, Taylor & Francis Journals, vol. 19(4), pages 200-213, October.
    • Handle: RePEc:taf:mpopst:v:19:y:2012:i:4:p:200-213
    DOI: 10.1080/08898480.2012.725379
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