IDEAS home Printed from https://ideas.repec.org/a/taf/gcmbxx/v27y2024i13p1944-1948.html
   My bibliography  Save this article

Development of a computational-experimental framework for enhanced mechanical characterization and cross-species comparison of the articular cartilage superficial zone

Author

Listed:
  • Steven P. Mell
  • Catherine Yuh
  • Thomas Nagel
  • Susan Chubinskaya
  • Hannah J. Lundberg
  • Markus A. Wimmer

Abstract

To provide a better understanding of the contribution of specific constituents (i.e. proteoglycan, collagen, fluid) to the mechanical behavior of the superficial zone of articular cartilage, a complex biological tissue with several time-dependent properties, a finite element model was developed. Optimization was then used to fit the model to microindentation experiments. We used this model to compare superficial zone material properties of mature human vs. immature bovine articular cartilage. Non-linearity and stiffness of the fiber-reinforced component of the model differed between human and bovine tissue. This may be due to the more complex collagen architecture in mature tissue and is of interest to investigate in future work.

Suggested Citation

  • Steven P. Mell & Catherine Yuh & Thomas Nagel & Susan Chubinskaya & Hannah J. Lundberg & Markus A. Wimmer, 2024. "Development of a computational-experimental framework for enhanced mechanical characterization and cross-species comparison of the articular cartilage superficial zone," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 27(13), pages 1944-1948, October.
    • Handle: RePEc:taf:gcmbxx:v:27:y:2024:i:13:p:1944-1948
    DOI: 10.1080/10255842.2023.2255712
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1080/10255842.2023.2255712
    Download Restriction: Access to full text is restricted to subscribers.
    File URL: https://libkey.io/10.1080/10255842.2023.2255712?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:taf:gcmbxx:v:27:y:2024:i:13:p:1944-1948. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Chris Longhurst (email available below). General contact details of provider: http://www.tandfonline.com/gcmb .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.