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Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation

Author

Listed:
  • Violeta Carvalho
  • Nelson Rodrigues
  • Ricardo Ribeiro
  • Pedro F. Costa
  • José C. F. Teixeira
  • Rui A. Lima
  • Senhorinha F. C. F. Teixeira

Abstract

Atherosclerosis is a progressive disease that can significantly reduce blood supply to vital organs, being one of the main causes of death worldwide. In this work, a numerical and experimental study in 3D printed stenotic coronary arteries, considering both steady and pulsatile blood flow conditions, is presented. The results revealed that a degree of stenosis superior to 50% creates disturbed flows downstream of the contraction, with an accented increase in the wall shear stress measurements at the stenosis throat. Finally, the multiphase mixture was investigated and compared with a single-phase modelling, and only slight differences were observed right after the stenosis throat.

Suggested Citation

  • Violeta Carvalho & Nelson Rodrigues & Ricardo Ribeiro & Pedro F. Costa & José C. F. Teixeira & Rui A. Lima & Senhorinha F. C. F. Teixeira, 2021. "Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 24(6), pages 623-636, April.
  • Handle: RePEc:taf:gcmbxx:v:24:y:2021:i:6:p:623-636
    DOI: 10.1080/10255842.2020.1842377
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