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Flow analysis of aortic dissection: comparison of inflow boundary conditions for computational models based on 4D PCMRI and Doppler ultrasound

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  • Zhenfeng Li
  • Shichao Liang
  • Huanming Xu
  • Minjia Zhu
  • Yuqian Mei
  • Jiang Xiong
  • Duanduan Chen

Abstract

Computational hemodynamics quantifying the flow environment is an important tool in understanding aortic dissection. In this study, various inflow boundaries were applied on a patient-specific model and compared to the individualized velocimetry. The results indicated that the computations generally overestimated the flow volume and underestimated the wall shear stress. By quantifying the accuracy of the simulation results, two inflow settings were suggested. One was individualized, the PCMRI-extracted 4D flow information, and the other was averaged by healthy data, the ultrasound-extracted averaged flow waveform with parabolic velocity profile. This study might contribute to improving the precise computation of aortic dissection hemodynamics.

Suggested Citation

  • Zhenfeng Li & Shichao Liang & Huanming Xu & Minjia Zhu & Yuqian Mei & Jiang Xiong & Duanduan Chen, 2021. "Flow analysis of aortic dissection: comparison of inflow boundary conditions for computational models based on 4D PCMRI and Doppler ultrasound," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 24(11), pages 1251-1262, September.
    • Handle: RePEc:taf:gcmbxx:v:24:y:2021:i:11:p:1251-1262
    DOI: 10.1080/10255842.2021.1876036
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