Regional assessment of vascular morphology and hemodynamics: methodology and evaluation for abdominal aortic aneurysms after endovascular repair

Abdominal aortic aneurysm is a deadly disease that can be treated with different endovascular devices that will distinctly alter the aortic morphology. Computational methods can be used to understand the effect of anatomical changes on aortic hemodynamics. We propose a standardized method to assess morphological and hemodynamic changes of the abdominal aorta through the longitudinal axis of the vessel. Patient-specific CFD simulations were used to quantify these changes for two different endografts before and after surgery. Differences in cross-sectional area, blood pressure, peak blood velocity, wall shear stress, and retrograde blood flow were accurately evidenced with the proposed methodology.