IDEAS home Printed from https://ideas.repec.org/a/spr/pharmo/v8y2024i6d10.1007_s41669-024-00517-3.html
   My bibliography  Save this article

A Systematic Review of the Impact of Spinal Cord Injury on Costs and Health-Related Quality of Life

Author

Listed:
  • Modou Diop

    (Hospinnomics (Paris School of Economics & Assistance Publique - Hôpitaux de Paris))

  • David Epstein

    (University of Granada)

Abstract

Objective To systematically review the health-related quality of life (HRQoL) burden and costs of spinal cord injury (SCI) on health services, patients and wider society. Methods A systematic review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement was conducted in March 2021 through Scopus, PubMed and Embase databases. Inclusion criteria were quantitative studies on SCI reporting healthcare costs, social costs and/or HRQoL measured with the Euroqol EQ-5D or Short-Form 36. Risk of bias was assessed using the QualSyst tool. Descriptive analyses, random-effects direct meta-analysis and random-effects meta-regression were conducted. Results A total of 67 studies were eligible for inclusion. SCI individuals tend to report higher HRQoL in mental than physical dimensions of the Short-Form 36. Neurological level of SCI negatively affects HRQoL. Cross-sectional studies find employment is associated with better HRQoL, but the effect is not observed in longitudinal studies. The estimated lifetime expenditure per individual with SCI ranged from US$0.7 million to US$2.5 million, with greater costs associated with earlier age at injury, neurological level, United States of America healthcare setting and the inclusion of non-healthcare items in the study. Conclusions SCI is associated with low HRQoL on mobility and physical dimensions. Mental health scores tend to be greater than physical scores, and most dimensions of HRQoL appear to improve over time, at least over the first year. SCI is associated with high costs which vary by country. Clinical Trials Registration This review was registered in PROSPERO (registration number: CRD42021235801).

Suggested Citation

  • Modou Diop & David Epstein, 2024. "A Systematic Review of the Impact of Spinal Cord Injury on Costs and Health-Related Quality of Life," PharmacoEconomics - Open, Springer, vol. 8(6), pages 793-808, November.
    • Handle: RePEc:spr:pharmo:v:8:y:2024:i:6:d:10.1007_s41669-024-00517-3
    DOI: 10.1007/s41669-024-00517-3
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s41669-024-00517-3
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1007/s41669-024-00517-3?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:pharmo:v:8:y:2024:i:6:d:10.1007_s41669-024-00517-3. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.