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Cost-Effectiveness Analysis of Prognostic Gene Expression Signature-Based Stratification of Early Breast Cancer Patients

Author

Listed:
  • Patricia Blank
  • Martin Filipits
  • Peter Dubsky
  • Florian Gutzwiller
  • Michael Lux
  • Jan Brase
  • Karsten Weber
  • Margaretha Rudas
  • Richard Greil
  • Sibylle Loibl
  • Thomas Szucs
  • Ralf Kronenwett
  • Matthias Schwenkglenks
  • Michael Gnant

Abstract

Our study suggests that molecular markers can be sensibly combined with clinical guidelines to determine the risk profile of adjuvant breast cancer patients. Compared with the current German best practice (German-S3), combinations of EPclin with the St. Gallen, German-S3 or NCCN guideline and EPclin alone were dominant from the perspective of the German healthcare system. Copyright The Author(s) 2015

Suggested Citation

  • Patricia Blank & Martin Filipits & Peter Dubsky & Florian Gutzwiller & Michael Lux & Jan Brase & Karsten Weber & Margaretha Rudas & Richard Greil & Sibylle Loibl & Thomas Szucs & Ralf Kronenwett & Mat, 2015. "Cost-Effectiveness Analysis of Prognostic Gene Expression Signature-Based Stratification of Early Breast Cancer Patients," PharmacoEconomics, Springer, vol. 33(2), pages 179-190, February.
  • Handle: RePEc:spr:pharme:v:33:y:2015:i:2:p:179-190
    DOI: 10.1007/s40273-014-0227-x
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    References listed on IDEAS

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    1. Peasgood, T & Ward, S & Brazier, J, 2010. "A review and meta-analysis of health state utility values in breast cancer," MPRA Paper 29950, University Library of Munich, Germany.
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