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Cost-Effectiveness Analyses in Multiple Sclerosis: A Review of Modelling Approaches

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  • Shien Guo
  • Christopher Pelligra
  • Catherine Saint-Laurent Thibault
  • Luis Hernandez
  • Anuraag Kansal

Abstract

The growing number of disease-modifying treatments (DMTs) for patients with multiple sclerosis (MS) and the high acquisition costs of these DMTs are likely to increase the demand for information on their cost effectiveness. To improve the comparability and applicability of the findings from future cost-effectiveness analyses, it would be useful to have a clear understanding of the methodological challenges of modelling the cost effectiveness of DMTs in MS and the different approaches taken by such studies to date. In contrast to previous review studies, this review focuses on long-term time horizon (≥10 years) simulation-based cost-effectiveness analyses with homogeneous contexts of analysis (i.e. those with similar study objectives, comparators, and target populations) published over the past decade. By doing so, it provides a clearer picture of how modelling approaches taken in the existing studies truly differ across studies, and reveals major areas for improvement in conducting future cost-effectiveness analyses of DMTs for patients with MS. Copyright Springer International Publishing Switzerland 2014

Suggested Citation

  • Shien Guo & Christopher Pelligra & Catherine Saint-Laurent Thibault & Luis Hernandez & Anuraag Kansal, 2014. "Cost-Effectiveness Analyses in Multiple Sclerosis: A Review of Modelling Approaches," PharmacoEconomics, Springer, vol. 32(6), pages 559-572, June.
    • Handle: RePEc:spr:pharme:v:32:y:2014:i:6:p:559-572
    DOI: 10.1007/s40273-014-0150-1
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    1. Annie Hawton & James Shearer & Elizabeth Goodwin & Colin Green, 2013. "Squinting Through Layers of Fog: Assessing the Cost Effectiveness of Treatments for Multiple Sclerosis," Applied Health Economics and Health Policy, Springer, vol. 11(4), pages 331-341, August.
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