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Clinical and Economic Impact of Substituting Dexmedetomidine for Propofol due to a US Drug Shortage: Examination of Coronary Artery Bypass Graft Patients at an Urban Medical Centre

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  • Brandi Thoma
  • Julius Li
  • Cara McDaniel
  • Cindy Wordell
  • Nicholas Cavarocchi
  • Laura Pizzi

Abstract

Findings suggest that use of dexmedetomidine as an alternative to propofol for sedation of CABG patients post-operatively contributes to reduced mechanical ventilation time, ICU LOS and post-operative LOS. Higher drug costs resulting from the propofol shortage were offset by savings in post-operative room and board costs. Additional savings may be possible by preventing medical complications to the extent possible. Copyright Springer International Publishing Switzerland 2014

Suggested Citation

  • Brandi Thoma & Julius Li & Cara McDaniel & Cindy Wordell & Nicholas Cavarocchi & Laura Pizzi, 2014. "Clinical and Economic Impact of Substituting Dexmedetomidine for Propofol due to a US Drug Shortage: Examination of Coronary Artery Bypass Graft Patients at an Urban Medical Centre," PharmacoEconomics, Springer, vol. 32(2), pages 149-157, February.
    • Handle: RePEc:spr:pharme:v:32:y:2014:i:2:p:149-157
    DOI: 10.1007/s40273-013-0116-8
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    Cited by:

    1. Jonathan Minh Phuong & Jonathan Penm & Betty Chaar & Lachlan Daniel Oldfield & Rebekah Moles, 2019. "The impacts of medication shortages on patient outcomes: A scoping review," PLOS ONE, Public Library of Science, vol. 14(5), pages 1-17, May.

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