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Oral Antiplatelet Therapy in Secondary Prevention of Cardiovascular Events

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  • Bart Heeg
  • Joep Damen
  • Ben Hout

Abstract

The cost-effectiveness estimates presented in this article support the NICE guidelines for the use of antiplatelets for the prevention of cardiovascular events. Based on these pharmacoeconomic data alone, aspirin should be prescribed for primary or secondary prevention among patients at high risk of cardiovascular events, dipyridamole for the secondary prevention of stroke (for a maximum of 5 years), and clopidogrel for the treatment of symptomatic cardiovascular disease or acute coronary syndrome (for a maximum of 2 years). The cost effectiveness of antiplatelets hinges on the patient’s initial risk, the risk reduction associated with treatment, and the price of the treatment. Evidence suggests that the cost effectiveness of antiplatelets can be optimized by individualising the treatment decision based on patient risk and expected risk reduction. Copyright Adis Data Information BV 2007

Suggested Citation

  • Bart Heeg & Joep Damen & Ben Hout, 2007. "Oral Antiplatelet Therapy in Secondary Prevention of Cardiovascular Events," PharmacoEconomics, Springer, vol. 25(12), pages 1063-1082, December.
    • Handle: RePEc:spr:pharme:v:25:y:2007:i:12:p:1063-1082
    DOI: 10.2165/00019053-200725120-00007
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    References listed on IDEAS

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    1. Anna Ringborg & Peter Lindgren & Bengt Jönsson, 2005. "The cost-effectiveness of dual oral antiplatelet therapy following percutaneous coronary intervention," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 6(4), pages 354-362, December.
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    Cited by:

    1. J. Logman & Bart Heeg & Johan Herlitz & Ben Hout, 2010. "Costs and consequences of clopidogrel versus aspirin for secondary prevention of ischaemic events in (high-risk) atherosclerotic patients in Sweden," Applied Health Economics and Health Policy, Springer, vol. 8(4), pages 251-265, July.

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