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The Enhanced Double Digest Problem for DNA Physical Mapping

Author

Listed:
  • Ming-Yang Kao

    (Yale University)

  • Jared Samet

    (Yale College)

  • Wing-Kin Sung

    (Yale University)

Abstract

The double digest problem is a common NP-hard approach to constructing physical maps of DNA sequences. This paper presents a new approach called the enhanced double digest problem. Although this new problem is also NP-hard, it can be solved in linear time in certain theoretically interesting cases.

Suggested Citation

  • Ming-Yang Kao & Jared Samet & Wing-Kin Sung, 2003. "The Enhanced Double Digest Problem for DNA Physical Mapping," Journal of Combinatorial Optimization, Springer, vol. 7(1), pages 69-78, March.
  • Handle: RePEc:spr:jcomop:v:7:y:2003:i:1:d:10.1023_a:1021946523069
    DOI: 10.1023/A:1021946523069
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