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Economic evaluation of human papillomavirus vaccination in the Global South: a systematic review

Author

Listed:
  • Saba Abidi

    (Delhi Pharmaceutical Sciences and Research University)

  • Satyanarayana Labani

    (Indian Council of Medical Research – National Institute of Cancer Prevention and Research)

  • Aastha Singh

    (Delhi Pharmaceutical Sciences and Research University)

  • Smita Asthana

    (Indian Council of Medical Research – National Institute of Cancer Prevention and Research)

  • Puneeta Ajmera

    (Delhi Pharmaceutical Sciences and Research University)

Abstract

Objectives Many reviews have been conducted on the economic evaluation of the HPV vaccine in global north countries. But there is a dearth of such reviews in the Global South countries. Hence, this systematic review aims to summarize studies done in these countries. Methods Four databases PubMed, Embase, Cochrane Library, and Google Scholar from 2009 to 2019 were searched for economic evaluations on HPV vaccination in the Global South countries. PRISMA guidelines were followed to include full-text articles. 40 original articles were shortlisted for full-text review. Results Studies had varied models, assumptions, and results according to different scenarios. Most studies concluded HPV vaccination to be cost-effective under varied scenarios and vaccine cost was the most influential parameter affecting the sensitivity analyses, consequently incremental cost-effectiveness ratio. A wide range in the cost-effectiveness ratio was observed in the included studies due to different study settings, populations, and inconsistencies in modeling practices (variations in methodological approaches). Conclusions This review suggests the introduction of HPV vaccination alone or in combination with screening according to different countries. The price of the vaccine should be economical and funds for the vaccine should be provided by public sector firms.

Suggested Citation

  • Saba Abidi & Satyanarayana Labani & Aastha Singh & Smita Asthana & Puneeta Ajmera, 2020. "Economic evaluation of human papillomavirus vaccination in the Global South: a systematic review," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 65(7), pages 1097-1111, September.
    • Handle: RePEc:spr:ijphth:v:65:y:2020:i:7:d:10.1007_s00038-020-01431-1
    DOI: 10.1007/s00038-020-01431-1
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    1. Johanna Aponte-González & Luisa Fajardo-Bernal & Jorge Diaz & Javier Eslava-Schmalbach & Oscar Gamboa & Joel W Hay, 2013. "Cost-Effectiveness Analysis of the Bivalent and Quadrivalent Human Papillomavirus Vaccines from a Societal Perspective in Colombia," PLOS ONE, Public Library of Science, vol. 8(11), pages 1-1, November.
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