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Analgetika und laxantien als risikofaktoren für krebs der ableitenden Harnwege—Ergebnisse der Berliner Urothelkarzinom-Studie (BUS)

Author

Listed:
  • Elisabeth Bronder
  • Andreas Klimpel
  • Uwe Helmert
  • Eberhard Greiser
  • Martin Molzahn
  • Wolfgang Pommer

Abstract

Une étude rétrospective par cas-témoins (la BUS) examina d'analgésiques et laxatifs comme des risques pour les carcinomes des voies urinaires (1990–1995). Spécial pour les carcinomes du bassinets des reins on a constaté des risques spécifiques des substances et des doses d'analgésiques antipyrétiques des calmants combinés en particulier. On a analysé les substances analgésiques: phénacétine, paracétamol, acide acétylsalicile et les pyrazolones. L'existence d'un risque des laxatifs de type «laxatifs de contact» appelés aussi «stimulants» est un fait nouveau. Ces laxatifs qu'ils proviennent de substances chimiques ou végétales anthranoides peuvent favoriser l'évolution du cancer des voies urinaires. On compte avec les plus grands risques pour le végétal Senna. Les laxatifs ainsi que les calmants antipyrétiques font partie des préparations typiques de médicaments OTC («Over the counter»), ils représentent sur le marché des médicaments une grande partie de la vente. L'étude présente apporte ainsi une nouvelle contribution á l'évaluation des risques des médicaments OTC dans les cas de tumeurs des voies urinaires. Copyright Birkhäuser Verlag 1999

Suggested Citation

  • Elisabeth Bronder & Andreas Klimpel & Uwe Helmert & Eberhard Greiser & Martin Molzahn & Wolfgang Pommer, 1999. "Analgetika und laxantien als risikofaktoren für krebs der ableitenden Harnwege—Ergebnisse der Berliner Urothelkarzinom-Studie (BUS)," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 44(3), pages 117-125, May.
    • Handle: RePEc:spr:ijphth:v:44:y:1999:i:3:p:117-125
    DOI: 10.1007/BF01299400
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