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The epidemiology, economics and quality of life burden of age-related macular degeneration in France, Germany, Italy and the United Kingdom

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  • J. Bonastre
  • C. Le Pen
  • P. Anderson
  • A. Ganz
  • P. Berto
  • G. Berdeaux

Abstract

Age-related macular degeneration (AMD) is a major public health issue, but little is known about the economics of the disease. This contribution describes the epidemiology and the economics of AMD in four European countries: France, Germany, Italy and the United Kingdom (UK). We reviewed published information on AMD, including guidelines, official statistics, and local literature and interviewed AMD experts. All available health-related quality of life studies (HRQoL) on AMD were also reviewed. Data collection focused on epidemiology, medical management and resource use (both medical and non-medical items). Prevalence of AMD among persons older than 65 years is 8% and increases with age. There are two forms of the disease: atrophic (80–85% of AMD cases) and exudative, which is characterised by choroidal neovascularisation (CNV; 15–20% of AMD cases). No treatment for the atrophic form is available. Laser photocoagulation is the mainstay of treatment for CNV, although less than 30% of persons with CNV can benefit from it. Photodynamic therapy (PDT), a new treatment for CNV, reduces the risk of vision loss in forms with predominantly visible lesions. Several other new procedures are also under development. Rehabilitation and low-vision aids are useful palliative interventions when there is a residual visual acuity. The yearly budget impact of AMD was found to be between 51.3 and 101.1 million euros in the four countries studied. Information on social services and resource use was scant and little is reported on the impact of AMD on HRQoL. Economic studies of AMD should be conducted in order to assist public health decision making. Copyright Springer-Verlag Berlin Heidelberg 2002

Suggested Citation

  • J. Bonastre & C. Le Pen & P. Anderson & A. Ganz & P. Berto & G. Berdeaux, 2002. "The epidemiology, economics and quality of life burden of age-related macular degeneration in France, Germany, Italy and the United Kingdom," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 3(2), pages 94-102, June.
    • Handle: RePEc:spr:eujhec:v:3:y:2002:i:2:p:94-102
    DOI: 10.1007/s10198-002-0104-y
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    Cited by:

    1. Kollerup, Anna & Wadmann, Sarah & Bek, Toke & Kjellberg, Jakob, 2022. "National clinical guidelines and treatment centralization do not guarantee consistency in healthcare delivery. A mixed-methods study of wet age-related macular degeneration treatment in Denmark," Health Policy, Elsevier, vol. 126(12), pages 1291-1302.
    2. Livio Garattini & Emanuela Castelnuovo & Paolo Lanzetta & Cecilia Viscarra & Elena Ricci & Fabio Parazzini, 2004. "Direct medical costs of age-related macular degeneration in Italian hospital ophthalmology departments," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 5(1), pages 22-27, February.
    3. Bennion, Amy E. & Shaw, Rachel L. & Gibson, Jonathan M., 2012. "What do we know about the experience of age related macular degeneration? A systematic review and meta-synthesis of qualitative research," Social Science & Medicine, Elsevier, vol. 75(6), pages 976-985.
    4. Thomas, Dominik & Weegen, Lennart & Walendzik, Anke & Wasem, Jürgen & Jahn, Rebecca, 2011. "Comparative analysis of delivery of primary eye care in three European countries," IBES Diskussionsbeiträge 189, University of Duisburg-Essen, Institute of Business and Economic Studie (IBES).

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