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The EORTC QLU-C10D: the Hong Kong valuation study

Author

Listed:
  • Richard Huan Xu

    (The Hong Kong Polytechnic University
    The Chinese University of Hong Kong)

  • Eliza Lai-yi Wong

    (The Chinese University of Hong Kong)

  • Nan Luo

    (The National University of Singapore)

  • Richard Norman

    (Curtin University)

  • Jens Lehmann

    (Medical University of Innsbruck)

  • Bernhard Holzner

    (Medical University of Innsbruck)

  • Madeleine T. King

    (University of Sydney)

  • Georg Kemmler

    (Medical University of Innsbruck)

Abstract

Objective The EORTC QLU-C10D is a new preference-based measure derived from the EORTC QLQ-C30. Country-specific value sets are required to support the cost-utility analysis of cancer-related interventions. This study aimed to generate an EORTC QLU-C10 value set for Hong Kong (HK). Methods A HK online panel was quota-sampled to achieve an adult general population sample representative by sex and age. Participants were invited to complete an online discrete choice experiment survey. Each participant was asked to complete 16 choice-pairs, randomly assigned from a total of 960 choice-pairs, each comprising two QLU-C10D health states and a duration attribute. Conditional and mixed logistic regression analyses were used to analyse the data. Results The analysis included data from 1041 respondents who had successfully completed the online survey. The distribution of sex did not differ from that of the general population, but a significant difference was found among age groups. A weighting analysis for non-representative variable (age) was used. Utility decrements were generally monotonic, with the largest decrements for physical functioning (− 0.308), role functioning (− 0.165), and pain (− 0.161). The mean QLU-C10D utility score of the participants was 0.804 (median = 0.838, worst to best = − 0.169 to 1). The value of the worst health state was − 0.223, which was sufficiently lower than 0 (being dead). Conclusions This study established HK utility weights for the QLU-C10D, which can facilitate cost-utility analyses across cancer-related health programmes and technologies.

Suggested Citation

  • Richard Huan Xu & Eliza Lai-yi Wong & Nan Luo & Richard Norman & Jens Lehmann & Bernhard Holzner & Madeleine T. King & Georg Kemmler, 2024. "The EORTC QLU-C10D: the Hong Kong valuation study," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 25(5), pages 889-901, July.
    • Handle: RePEc:spr:eujhec:v:25:y:2024:i:5:d:10.1007_s10198-023-01632-4
    DOI: 10.1007/s10198-023-01632-4
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    References listed on IDEAS

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    7. Dennis A. Revicki & Madeleine T. King & Rosalie Viney & A. Simon Pickard & Rebecca Mercieca-Bebber & James W. Shaw & Fabiola Müller & Richard Norman, 2021. "United States Utility Algorithm for the EORTC QLU-C10D, a Multiattribute Utility Instrument Based on a Cancer-Specific Quality-of-Life Instrument," Medical Decision Making, , vol. 41(4), pages 485-501, May.
    8. Aureliano Paolo Finch & Eva Gamper & Richard Norman & Rosalie Viney & Bernhard Holzner & Madeleine King & Georg Kemmler, 2021. "Estimation of an EORTC QLU-C10 Value Set for Spain Using a Discrete Choice Experiment," PharmacoEconomics, Springer, vol. 39(9), pages 1085-1098, September.
    9. Matthew Kennedy-Martin & Bernhard Slaap & Michael Herdman & Mandy Reenen & Tessa Kennedy-Martin & Wolfgang Greiner & Jan Busschbach & Kristina S. Boye, 2020. "Which multi-attribute utility instruments are recommended for use in cost-utility analysis? A review of national health technology assessment (HTA) guidelines," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 21(8), pages 1245-1257, November.
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    More about this item

    Keywords

    Utility weights; Discrete choice experiment; EORTC QLQ-C30; QLU-C10D; Hong Kong; Quality of life; Decision making;
    All these keywords.

    JEL classification:

    • I15 - Health, Education, and Welfare - - Health - - - Health and Economic Development

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