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Hospital resource utilisation from HPV-related diseases in England: a real-world cost analysis

Author

Listed:
  • G. Fabiano

    (Kingston University
    University of Oxford)

  • A. Marcellusi

    (Kingston University
    University of Rome “Tor Vergata”)

  • F. S. Mennini

    (Kingston University
    University of Rome “Tor Vergata”)

  • P. Sciattella

    (University of Rome “Tor Vergata”)

  • G. Favato

    (Kingston University)

Abstract

Background and objective HPV (human papillomavirus) is the virus most often responsible for sexually transmitted infections. The burden of HPV-related diseases on hospital resources represents a major public health problem. The objective of this study was to quantify the lifetime economic burden of HPV-related diseases based on hospital resources from the perspective of National Health Service (NHS) in England. Methods Patients’ data were extracted, anonymised and aggregated by NHS digital from Hospital Episode Statistics (HES) database of patients admitted in 2015 and followed for three years. Data on hospitalizations were identified according to the International Classification of Diseases (ICD-10 CM). Health Resource Group (HRG) tariffs and National Reference Costs were used to estimate the hospitalization costs of anal, cervical, genital, oropharyngeal cancers as well as anogenital warts and cervical dysplasia. Results A total of 19,296 hospitalized patients were included in the estimation model, (39% was male and 61% female. At admission, the average age was 60 and 50 years old, respectively). Life-time costs per patients diagnosed with oropharyngeal cancer were £16,911 (£17,142 for male and £16,334 for female), penile cancer £12,539, vaginal cancer £12,676, anal cancer £13.773 (£12,590 for male, £14,525 for female). Cervical cancer accounted for £12,721, whereas cervical dysplasia for £3932. Resource used for hospitalized patients with anogenital warts was equal to £872 (£884 and £856 for men and women, respectively). On average, outpatient accounted for 39% of the total lifetime costs. Conclusion The results of this study highlight that a substantial amount of resources is utilized for the treatment of HPV-related diseases at hospital level in England. These measures have the potential to inform policy decisions to ensure an optimal use of the NHS resources.

Suggested Citation

  • G. Fabiano & A. Marcellusi & F. S. Mennini & P. Sciattella & G. Favato, 2023. "Hospital resource utilisation from HPV-related diseases in England: a real-world cost analysis," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(1), pages 75-80, February.
    • Handle: RePEc:spr:eujhec:v:24:y:2023:i:1:d:10.1007_s10198-022-01453-x
    DOI: 10.1007/s10198-022-01453-x
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    References listed on IDEAS

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    1. A. Marcellusi & R. Viti & A. Mecozzi & F. Mennini, 2016. "The direct and indirect cost of diabetes in Italy: a prevalence probabilistic approach," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 17(2), pages 139-147, March.
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    More about this item

    Keywords

    Human papillomavirus; Real world; Resource utilization; Hospital episodes statistics; England;
    All these keywords.

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General
    • I11 - Health, Education, and Welfare - - Health - - - Analysis of Health Care Markets
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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