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Simulating lifestyle and medical interventions to prevent type-2 diabetes: an economic evaluation for Belgium

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  • Désirée Vandenberghe

    (Ghent University)

Abstract

By 2040, over half a billion people globally are expected to have diabetes. This disease implies a loss in life quality and comes with a significant financial impact. To avoid prevalence increases in the main category of diabetes—type-2 diabetes (T-2D)—, preventive action among high-risk groups is necessary. Lifestyle and medical interventions with metformin among prediabetic individuals show strong potential to decrease or delay T-2D. The aim of this paper is to evaluate the cost-effectiveness and budget impact of a nation-wide implementation of these interventions, between 2020 and 2040, in Belgium. This is done through a dynamic, non-homogeneous, semi-Markov model which simulates prevalence and costs of a type of prediabetes (impaired glucose tolerance or IGT) and T-2D in Belgium. High-risk individuals are first screened; individuals with IGT then enroll in a lifestyle or metformin program. Compared to no intervention, both programs are very cost effective from the perspective of the health care system and cost-saving from a broader societal perspective. Both interventions require an initial, affordable government investment and later yield government savings. The lifestyle program is a cost-effective alternative to the metformin intervention and may yield additional benefits through, for example, improvements in mental health.

Suggested Citation

  • Désirée Vandenberghe, 2022. "Simulating lifestyle and medical interventions to prevent type-2 diabetes: an economic evaluation for Belgium," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 23(2), pages 237-248, March.
    • Handle: RePEc:spr:eujhec:v:23:y:2022:i:2:d:10.1007_s10198-021-01362-5
    DOI: 10.1007/s10198-021-01362-5
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    References listed on IDEAS

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    1. Fabrice Murtin & Johan Mackenbach & Domantas Jasilionis & Marco Mira d’Ercole, 2017. "Inequalities in longevity by education in OECD countries: Insights from new OECD estimates," OECD Statistics Working Papers 2017/2, OECD Publishing.
    2. Till Seuring & Olga Archangelidi & Marc Suhrcke, 2015. "The Economic Costs of Type 2 Diabetes: A Global Systematic Review," PharmacoEconomics, Springer, vol. 33(8), pages 811-831, August.
    3. Roberts, Samantha & Barry, Eleanor & Craig, Dawn & Airoldi, Mara & Bevan, Gwyn & Greenhalgh, Trisha, 2017. "Preventing type 2 diabetes: systematic review of studies of cost-effectiveness of lifestyle programmes and metformin, with and without screening, for pre-diabetes," LSE Research Online Documents on Economics 86468, London School of Economics and Political Science, LSE Library.
    Full references (including those not matched with items on IDEAS)

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    More about this item

    Keywords

    Type-2 diabetes; Prediabetes; Lifestyle intervention; Metformin intervention; Cost effectiveness; Budget impact;
    All these keywords.

    JEL classification:

    • I11 - Health, Education, and Welfare - - Health - - - Analysis of Health Care Markets
    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • C63 - Mathematical and Quantitative Methods - - Mathematical Methods; Programming Models; Mathematical and Simulation Modeling - - - Computational Techniques
    • D62 - Microeconomics - - Welfare Economics - - - Externalities

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