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Work productivity loss and indirect costs associated with new cardiovascular events in high-risk patients with hyperlipidemia: estimates from population-based register data in Sweden

Author

Listed:
  • J. Banefelt

    (Quantify Research)

  • S. Hallberg

    (Quantify Research)

  • K. M. Fox

    (Strategic Healthcare Solutions, LLC)

  • J. Mesterton

    (Quantify Research
    Karolinska Institute)

  • C. J. Paoli

    (Amgen Inc.)

  • G. Johansson

    (Uppsala University)

  • L.-Å. Levin

    (Linköping University)

  • P. Sobocki

    (Karolinska Institute
    IMS Health)

  • S. R. Gandra

    (Amgen Inc.)

Abstract

Objectives To estimate productivity loss and associated indirect costs in high-risk patients treated for hyperlipidemia who experience cardiovascular (CV) events. Methods Retrospective population-based cohort study conducted using Swedish medical records linked to national registers. Patients were included based on prescriptions of lipid-lowering therapy between 1 January 2006 and 31 December 2011 and followed until 31 December 2012 for identification of CV events and estimation of work productivity loss (sick leave and disability pension) and indirect costs. Patients were stratified into two cohorts based on CV risk level: history of major cardiovascular disease (CVD) and coronary heart disease (CHD) risk equivalent. Propensity score matching was applied to compare patients with new events (cases) to patients without new events (controls). The incremental effect of CV events was estimated using a difference-in-differences design, comparing productivity loss among cases and controls during the year before and the year after the cases’ event. Results The incremental effect on indirect costs was largest in the CHD risk equivalent cohort (n = 2946) at €3119 (P value

Suggested Citation

  • J. Banefelt & S. Hallberg & K. M. Fox & J. Mesterton & C. J. Paoli & G. Johansson & L.-Å. Levin & P. Sobocki & S. R. Gandra, 2016. "Work productivity loss and indirect costs associated with new cardiovascular events in high-risk patients with hyperlipidemia: estimates from population-based register data in Sweden," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 17(9), pages 1117-1124, December.
    • Handle: RePEc:spr:eujhec:v:17:y:2016:i:9:d:10.1007_s10198-015-0749-y
    DOI: 10.1007/s10198-015-0749-y
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    References listed on IDEAS

    as
    1. Peter Lindgren & Thomas Kahan & Neil Poulter & Martin Buxton & Patrick Svarvar & Björn Dahlöf & Bengt Jönsson, 2007. "Utility loss and indirect costs following cardiovascular events in hypertensive patients: the ASCOT health economic substudy," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 8(1), pages 25-30, March.
    2. Drummond, Michael F. & Sculpher, Mark J. & Torrance, George W. & O'Brien, Bernie J. & Stoddart, Greg L., 2005. "Methods for the Economic Evaluation of Health Care Programmes," OUP Catalogue, Oxford University Press, edition 3, number 9780198529453.
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    More about this item

    Keywords

    Cardiovascular disease; Hyperlipidemia; Indirect costs; Productivity;
    All these keywords.

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior

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