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Exploring the relationship between EQ-5D, DLQI and PASI, and mapping EQ-5D utilities: a cross-sectional study in psoriasis from Hungary

Author

Listed:
  • Emese Herédi

    (University of Debrecen)

  • Fanni Rencz

    (Corvinus University of Budapest
    Semmelweis University)

  • Orsolya Balogh

    (Corvinus University of Budapest)

  • László Gulácsi

    (Corvinus University of Budapest)

  • Krisztina Herszényi

    (Semmelweis University)

  • Péter Holló

    (Semmelweis University)

  • Hajnalka Jókai

    (Semmelweis University)

  • Sarolta Kárpáti

    (Semmelweis University)

  • Márta Péntek

    (Corvinus University of Budapest)

  • Éva Remenyik

    (University of Debrecen)

  • Andrea Szegedi

    (University of Debrecen)

  • Valentin Brodszky

    (Corvinus University of Budapest)

Abstract

Background There is a growing interest in policy making for using utility measures and identifying algorithms to convert disease-specific measures into utilities. Objectives To analyse the relationship between EQ-5D, Dermatology Life Quality Index (DLQI) and Psoriasis Area and Severity Index (PASI) in psoriasis. To transform DLQI scores, and key clinical, demographic and health service utilisation variables into utilities. Methods A cross-sectional questionnaire survey of 200 consecutive adult patients with moderate to severe psoriasis was carried out in two Hungarian university clinics. The relationship between the outcome measures were analysed with correlations and with the known-groups method. Bivariate and multivariate regression algorithms on EQ-5D scores were formulated. Results The mean age of respondents was 51 years (SD = 12.9), 68.5 % were male, and 51.5 % received biological therapy. Median EQ-5D, DLQI, and PASI scores were 0.73, 3.0, and 3.45, respectively. EQ-5D showed a moderate correlation with the DLQI and with the PASI (r s = −0.48 and −0.43, p

Suggested Citation

  • Emese Herédi & Fanni Rencz & Orsolya Balogh & László Gulácsi & Krisztina Herszényi & Péter Holló & Hajnalka Jókai & Sarolta Kárpáti & Márta Péntek & Éva Remenyik & Andrea Szegedi & Valentin Brodszky, 2014. "Exploring the relationship between EQ-5D, DLQI and PASI, and mapping EQ-5D utilities: a cross-sectional study in psoriasis from Hungary," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 15(1), pages 111-119, May.
    • Handle: RePEc:spr:eujhec:v:15:y:2014:i:1:d:10.1007_s10198-014-0600-x
    DOI: 10.1007/s10198-014-0600-x
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    More about this item

    Keywords

    Psoriasis; Quality of life; EQ-5D; DLQI; Mapping;
    All these keywords.

    JEL classification:

    • I19 - Health, Education, and Welfare - - Health - - - Other

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