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Patient-Reported Reasons for Switching or Discontinuing Statin Therapy: A Mixed Methods Study Using Social Media

Author

Listed:
  • Su Golder

    (University of York)

  • Davy Weissenbacher

    (University of Pennsylvania)

  • Karen O’Connor

    (University of Pennsylvania)

  • Sean Hennessy

    (University of Pennsylvania)

  • Robert Gross

    (University of Pennsylvania)

  • Graciela Gonzalez Hernandez

    (University of Pennsylvania)

Abstract

Introduction Statin discontinuation can have major negative health consequences. Studying the reasons for discontinuation can be challenging as traditional data collection methods have limitations. We propose an alternative approach using social media. Methods We used natural language processing and machine learning to extract mentions of discontinuation of statin therapy from an online health forum, WebMD ( http://www.webmd.com ). We then extracted data according to themes and identified key attributes of the people posting for themselves. Results We identified 2121 statin reviews that contained information on discontinuing at least one named statin. Sixty percent of people posting declared themselves as female and the most common age category was 55–64 years. Over half the people taking statins did so for

Suggested Citation

  • Su Golder & Davy Weissenbacher & Karen O’Connor & Sean Hennessy & Robert Gross & Graciela Gonzalez Hernandez, 2022. "Patient-Reported Reasons for Switching or Discontinuing Statin Therapy: A Mixed Methods Study Using Social Media," Drug Safety, Springer, vol. 45(9), pages 971-981, September.
    • Handle: RePEc:spr:drugsa:v:45:y:2022:i:9:d:10.1007_s40264-022-01212-0
    DOI: 10.1007/s40264-022-01212-0
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    References listed on IDEAS

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    1. Su Golder & Karen Smith & Karen O’Connor & Robert Gross & Sean Hennessy & Graciela Gonzalez-Hernandez, 2021. "Correction to: A Comparative View of Reported Adverse Effects of Statins in Social Media, Regulatory Data, Drug Information Databases and Systematic Reviews," Drug Safety, Springer, vol. 44(2), pages 259-259, February.
    2. Su Golder & Karen Smith & Karen O’Connor & Robert Gross & Sean Hennessy & Graciela Gonzalez-Hernandez, 2021. "A Comparative View of Reported Adverse Effects of Statins in Social Media, Regulatory Data, Drug Information Databases and Systematic Reviews," Drug Safety, Springer, vol. 44(2), pages 167-179, February.
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    Cited by:

    1. Cristina Micale & Su Golder & Karen O’Connor & Davy Weissenbacher & Robert Gross & Sean Hennessy & Graciela Gonzalez-Hernandez, 2024. "Patient-Reported Reasons for Antihypertensive Medication Change: A Quantitative Study Using Social Media," Drug Safety, Springer, vol. 47(1), pages 81-91, January.

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