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Modelling Cost Effectiveness in Neovascular Age-Related Macular Degeneration: The Impact of Using Contrast Sensitivity vs. Visual Acuity

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  • Thomas Butt
  • Praveen Patel
  • Adnan Tufail
  • Gary Rubin

Abstract

There is considerable structural uncertainty associated with the choice of outcome for modelling the cost effectiveness of AMD treatments. Bevacizumab has a higher incremental QALY gain and more favourable incremental cost-effectiveness ratio when cost effectiveness is assessed using contrast sensitivity outcomes compared with using visual acuity outcomes. Previous cost-effectiveness analyses may have underestimated the cost effectiveness of anti-vascular endothelial growth factor (anti-VEGF) therapy. Copyright The Author(s) 2014

Suggested Citation

  • Thomas Butt & Praveen Patel & Adnan Tufail & Gary Rubin, 2014. "Modelling Cost Effectiveness in Neovascular Age-Related Macular Degeneration: The Impact of Using Contrast Sensitivity vs. Visual Acuity," Applied Health Economics and Health Policy, Springer, vol. 12(3), pages 289-297, June.
    • Handle: RePEc:spr:aphecp:v:12:y:2014:i:3:p:289-297
    DOI: 10.1007/s40258-014-0090-0
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    Cited by:

    1. Jordana K. Schmier & Carolyn K. Hulme-Lowe, 2016. "Cost-Effectiveness Models in Age-Related Macular Degeneration: Issues and Challenges," PharmacoEconomics, Springer, vol. 34(3), pages 259-272, March.
    2. Thomas Butt & Adnan Tufail & Gary Rubin, 2017. "Health State Utility Values for Age-Related Macular Degeneration: Review and Advice," Applied Health Economics and Health Policy, Springer, vol. 15(1), pages 23-32, February.
    3. Jordana Schmier & Carolyn Hulme-Lowe, 2016. "Cost-Effectiveness Models in Age-Related Macular Degeneration: Issues and Challenges," PharmacoEconomics, Springer, vol. 34(3), pages 259-272, March.

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