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Decision Analysis of Treatment Options in Pyriform Sinus Carcinoma

Author

Listed:
  • Dennis A. Plante
  • Jay F. Piccirillo
  • Robert A. Sofferman

Abstract

Decision analysis was used to evaluate the current treatment options for stage III squamous cell carcinoma of the pyriform sinus (surgery, radiation therapy, and combined surgery/ radiation therapy). Using published data, a decision tree was constructed based on quality- adjusted weeks of survival. With this model the combination of surgery and postoperative radiation therapy is preferred over either primary surgery or the combination of preoperative irradiation and surgery; primary radiation therapy is least favored. The decision is quite sensitive to the augmentation in survival that postoperative radiation therapy seems to provide over primary surgery. The decision is somewhat sensitive to the operative mortality rate and to the probability of disease-free survival following surgery. Quality of life issues emerge as important variables which need to be considered when planning treatment for patients with stage III pyriform sinus carcinoma. Key words: pyriform sinus carcinoma; hypopharyngeal carcinoma; decision analysis; quality of life. (Med Decis Making 7:74-83, 1987)

Suggested Citation

  • Dennis A. Plante & Jay F. Piccirillo & Robert A. Sofferman, 1987. "Decision Analysis of Treatment Options in Pyriform Sinus Carcinoma," Medical Decision Making, , vol. 7(2), pages 74-83, June.
    • Handle: RePEc:sae:medema:v:7:y:1987:i:2:p:74-83
    DOI: 10.1177/0272989X8700700203
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    References listed on IDEAS

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    1. George J. Cuchural & Andrew S. Levey & Stephen G. Pauker, 1984. "Kidney Failure or Cancer," Medical Decision Making, , vol. 4(1), pages 83-107, February.
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    Cited by:

    1. Gordon Hazen, 2004. "Multiattribute Structure for QALYs," Decision Analysis, INFORMS, vol. 1(4), pages 205-216, December.
    2. Anirban Basu & William Dale & Arthur Elstein & David Meltzer, 2009. "A linear index for predicting joint health‐states utilities from single health‐states utilities," Health Economics, John Wiley & Sons, Ltd., vol. 18(4), pages 403-419, April.
    3. Gordon B. Hazen & James M. Pellissier & Jayavel Sounderpandian, 1998. "Stochastic-Tree Models in Medical Decision Making," Interfaces, INFORMS, vol. 28(4), pages 64-80, August.
    4. Gordon Hazen & Emanuele Borgonovo & Xuefei Lu, 2023. "Information Density in Decision Analysis," Decision Analysis, INFORMS, vol. 20(2), pages 89-108, June.

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