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Catalog and Comparison of Societal Preferences (Utilities) for Lung Cancer Health States

Author

Listed:
  • Angela C. Tramontano
  • Deborah L. Schrag
  • Jennifer K. Malin
  • Melecia C. Miller
  • Jane C. Weeks
  • J. Shannon Swan
  • Pamela M. McMahon

Abstract

Background. The EQ-5D and SF-6D are 2 health-related quality-of-life indexes that provide preference-weighted measures for use in cost-effectiveness analyses. Methods. The National Cancer Institute’s Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium included the EQ-5D and SF-12v2 in their survey of newly diagnosed lung cancer patients. Utilities were calculated from patient-provided scores for each domain of the EQ-5D or the SF-6D. Utilities were calculated for categories of cancer type, stage, and treatment. Results. There were 5015 enrolled lung cancer patients with a baseline survey in CanCORS; 2396 (47.8%) completed the EQ-5D, and 2344 (46.7%) also completed the SF-12v2. The mean (standard deviation) utility from the EQ-5D was 0.78 (0.18), and from the SF-6D (derived from SF-12v2) was 0.68 (0.14). The EQ-5D demonstrated a ceiling effect, with 20% of patients reporting perfect scores, translating to a utility of 1.0. No substantial SF-6D floor effects were noted. Utilities increased with age and decreased with stage and comorbidities. Patient-reported (EQ-5D) visual analog scale scores for health status had a moderate ( r = 0.48, p

Suggested Citation

  • Angela C. Tramontano & Deborah L. Schrag & Jennifer K. Malin & Melecia C. Miller & Jane C. Weeks & J. Shannon Swan & Pamela M. McMahon, 2015. "Catalog and Comparison of Societal Preferences (Utilities) for Lung Cancer Health States," Medical Decision Making, , vol. 35(3), pages 371-387, April.
    • Handle: RePEc:sae:medema:v:35:y:2015:i:3:p:371-387
    DOI: 10.1177/0272989X15570364
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    Cited by:

    1. Mir-Masoud Pourrahmat & Ashley Kim & Anuraag R. Kansal & Marg Hux & Divya Pushkarna & Mir Sohail Fazeli & Karen C. Chung, 2021. "Health state utility values by cancer stage: a systematic literature review," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 22(8), pages 1275-1288, November.
    2. Steven D Criss & Lauren Palazzo & Tina R Watson & Adelle M Paquette & Keith Sigel & Juan Wisnivesky & Chung Yin Kong, 2020. "Cost-effectiveness of pembrolizumab for advanced non-small cell lung cancer patients with varying comorbidity burden," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-15, January.

    More about this item

    Keywords

    lung cancer; utilities; quality-of-life; EQ5D; SF6D;
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