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A Meta-Analysis of Nonpharmacological Interventions for People With Parkinson’s Disease

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  • JuHee Lee
  • MoonKi Choi
  • Yonju Yoo

Abstract

Nonpharmacological interventions are important in providing care for Parkinson’s disease (PD) patients. However, there is limited evidence related to their impacts on health-related quality of life (HRQOL). We aimed to examine the effectiveness of nonpharmacological interventions for improving the HRQOL of PD patients. Articles published in peer-reviewed journals from 2000 to 2015 were searched through electronic searching, computerized author searching, and footnote chasing. A meta-analysis was performed using the RevMan 5.3 program. Overall, effect size for the studies ( n = 18) was −4.17 with 95% confidence interval (CI) from −7.63 to −0.70 ( Z = 2.36, p = .02), indicating positive effects of nonpharmacological interventions on HRQOL. In subgroup analysis regarding the intervention types, the effect size of exercise programs was −5.73 with 95% CI of −11.36 to −0.10 ( Z = 2.00, p = .05). Thus, nonpharmacological interventions, and particularly exercise programs, were effective in improving the HRQOL of PD patients.

Suggested Citation

  • JuHee Lee & MoonKi Choi & Yonju Yoo, 2017. "A Meta-Analysis of Nonpharmacological Interventions for People With Parkinson’s Disease," Clinical Nursing Research, , vol. 26(5), pages 608-631, October.
    • Handle: RePEc:sae:clnure:v:26:y:2017:i:5:p:608-631
    DOI: 10.1177/1054773816655091
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