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Effects of nurse-led transitional care interventions for patients with heart failure on healthcare utilization: A meta-analysis of randomized controlled trials

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  • Minlu Li
  • Yuan Li
  • Qingtong Meng
  • Yinyin Li
  • Xiaomeng Tian
  • Ruixia Liu
  • Jinbo Fang

Abstract

Background: Heart failure (HF) imposes a substantial burden on patients and healthcare systems. Hospital-to-home transitional care, involving time-limited interventions delivered predominantly by nurses, was introduced to lighten this burden. This study aimed to examine the effectiveness and dose-response of nurse-led transitional care interventions (TCIs) on healthcare utilization among patients with HF. Methods: Health-related databases were systematically searched for articles published from January 2000 to June 2020. We included randomized controlled trials (RCTs) that compared nurse-led TCIs with usual care for adults hospitalized with HF and reported the following healthcare utilization outcomes: all-cause readmissions, HF-specific readmissions, emergency department visits, or length of hospital stay. Random-effects meta-analysis, meta-regression analysis, and dose-response analysis were performed to estimate the treatment effects and explain the heterogeneity. Results: Twenty-five RCTs including 8422 patients with HF were included. Nurse-led TCIs for patients with HF resulted in a mean 9% (RR = 0.91; 95% CI = 0.82 to 0.99; p = 0.04; I2 = 46%) and 29% (RR = 0.71; 95% CI = 0.60 to 0.84; p

Suggested Citation

  • Minlu Li & Yuan Li & Qingtong Meng & Yinyin Li & Xiaomeng Tian & Ruixia Liu & Jinbo Fang, 2021. "Effects of nurse-led transitional care interventions for patients with heart failure on healthcare utilization: A meta-analysis of randomized controlled trials," PLOS ONE, Public Library of Science, vol. 16(12), pages 1-16, December.
    • Handle: RePEc:plo:pone00:0261300
    DOI: 10.1371/journal.pone.0261300
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    References listed on IDEAS

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    1. Amro Qaddoura & Payam Yazdan-Ashoori & Conrad Kabali & Lehana Thabane & R Brian Haynes & Stuart J Connolly & Harriette Gillian Christine Van Spall, 2015. "Efficacy of Hospital at Home in Patients with Heart Failure: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(6), pages 1-15, June.
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