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Risk factors associated with the development of delirium in general ICU patients. A prospective observational study

Author

Listed:
  • Beatriz Lobo-Valbuena
  • Federico Gordo
  • Ana Abella
  • Sofía Garcia-Manzanedo
  • Maria-Mercedes Garcia-Arias
  • Inés Torrejón
  • David Varillas-Delgado
  • Rosario Molina

Abstract

Objective: We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. Material and methods: Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations. Results: 1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9–8.2), and (b) were more than 74 years old albeit having

Suggested Citation

  • Beatriz Lobo-Valbuena & Federico Gordo & Ana Abella & Sofía Garcia-Manzanedo & Maria-Mercedes Garcia-Arias & Inés Torrejón & David Varillas-Delgado & Rosario Molina, 2021. "Risk factors associated with the development of delirium in general ICU patients. A prospective observational study," PLOS ONE, Public Library of Science, vol. 16(9), pages 1-12, September.
  • Handle: RePEc:plo:pone00:0255522
    DOI: 10.1371/journal.pone.0255522
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