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Psychometric properties of Addenbrooke’s Cognitive Examination III (ACE-III): An item response theory approach

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  • Carlos Calderón
  • Christian Beyle
  • Oscar Véliz-García
  • Juan Bekios-Calfa

Abstract

The Addenbrooke’s Cognitive Examination III is one of the most widely used tests to assess cognitive impairment. Although previous studies have shown adequate levels of diagnostic utility to detect severe impairment, it has not shown sensitivity to detect mild decline. The aim of this study was to evaluate the psychometric properties of Addenbrooke’s Cognitive Examination III in a large sample of elderly people through Item Response Theory, due to the lack of studies using this approach. A cross-sectional study was conducted with 1164 people from the age of 60 upwards, of which 63 had a prior diagnosis of Alzheimer dementia. The results showed that, globally, the Addenbrooke’s Cognitive Examination III possesses adequate psychometrics properties. Furthermore, the information function test shows that the subscales have different sensitivity to different levels of impairment. These results can contribute to determining patterns of cognitive deterioration for the adequate detection of different levels of dementia. An optimized version is suggested which may be an economic alternative in the applied field.

Suggested Citation

  • Carlos Calderón & Christian Beyle & Oscar Véliz-García & Juan Bekios-Calfa, 2021. "Psychometric properties of Addenbrooke’s Cognitive Examination III (ACE-III): An item response theory approach," PLOS ONE, Public Library of Science, vol. 16(5), pages 1-16, May.
    • Handle: RePEc:plo:pone00:0251137
    DOI: 10.1371/journal.pone.0251137
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    1. Eleni-Zacharoula Georgiou & Maria Skondra & Marina Charalampopoulou & Panagiotis Felemegkas & Asimina Pachi & Georgia Stafylidou & Dimitrios Papazachariou & Robert Perneczky & Vasileios Thomopoulos & , 2023. "Validation of the test for finding word retrieval deficits (WoFi) in detecting Alzheimer's disease in a naturalistic clinical setting," European Journal of Ageing, Springer, vol. 20(1), pages 1-10, December.
    2. Mahdi Rezapour & Kelly Cuccolo & Christopher Veenstra & F. Richard Ferraro, 2021. "An Item Response Theory to Analyze the Psychological Impacts of Rail-Transport Delay," Sustainability, MDPI, vol. 13(12), pages 1-14, June.

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